Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9420350 | 1.00 | MAPK10 (0.50) | MAPK10HTTADRA2AL3MBTL1KDM4E | |
| SCHEMBL9420328 | 1.00 | MAPK10 (0.50) | MAPK10HTTADRA2AL3MBTL1KDM4E | |
| SCHEMBL9420340 | 1.00 | MAPK10 (0.50) | MAPK10HTTADRA2AL3MBTL1KDM4E | |
| SCHEMBL9420352 | 0.94 | MAPT (0.45) | MAPK10HTTADRA2AL3MBTL1KDM4E | |
| SCHEMBL9420368 | 0.92 | MAPK10 (0.47) | MAPK10HTTADRA2AL3MBTL1KDM4E | |
| SCHEMBL9420374 | 0.92 | MAPK10 (0.47) | MAPK10HTTADRA2AL3MBTL1KDM4E | |
| SCHEMBL9420345 | 0.84 | ALDH1A1 (0.40) | MAPK10HTTADRA2AL3MBTL1KDM4E | |
| SCHEMBL9420325 | 0.84 | ALDH1A1 (0.40) | MAPK10HTTADRA2AL3MBTL1KDM4E | |
| SCHEMBL9420356 | 0.80 | ALDH1A1 (0.60) | KDM4EALDH1A1MAPTGAAPTGS1 | |
| SCHEMBL9420337 | 0.79 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTPTGS1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354179-B1 | Thiouracils as stabilizers for polymers containing chlorine | CIBA GEIGY AG (CH) | 1994-08-17 | — | — | EP | claimed |