Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11557416 | 0.85 | CYP1A2 (0.50) | SMN1; SMN2TDP1LMNATSHR | |
| SCHEMBL445504 | 0.84 | CYP4F2 (0.50) | SMN1; SMN2TDP1LMNATSHRCYP4F2 | |
| SCHEMBL30427003 | 0.84 | CYP4F2 (0.50) | SMN1; SMN2TDP1LMNATSHRCYP4F2 | |
| SCHEMBL8871326 | 0.83 | LMNA (0.38) | SMN1; SMN2SERPINE1TDP1LMNATSHR | |
| SCHEMBL9420499 | 0.81 | SERPINE1 (0.49) | SMN1; SMN2SERPINE1TDP1LMNATSHR | |
| SCHEMBL9420514 | 0.81 | SERPINE1 (0.49) | SMN1; SMN2SERPINE1TDP1LMNATSHR | |
| SCHEMBL9420474 | 0.81 | SERPINE1 (0.49) | SMN1; SMN2SERPINE1TDP1LMNATSHR | |
| SCHEMBL8066511 | 0.80 | TDP1 (0.59) | SMN1; SMN2TDP1LMNAKMT2A | |
| SCHEMBL7613584 | 0.80 | CYP3A4 (0.46) | SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL40349 | 0.78 | CYP4F2 (0.51) | SMN1; SMN2TSHRCYP4F2CYP4A11CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328585-B1 | METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES | BIORESEARCH INC (US) | 1994-09-07 | — | — | EP | disclosed |
| EP-0328585-A4 | METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES | — | 1991-06-05 | — | — | EP | disclosed |
| EP-0328585-A1 | METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES | BIORESEARCH INC. (US) | 1989-08-23 | — | — | EP | disclosed |
| US-4829099-A | SURGERY, POLYISOCYANATES, POLYISOTHIOCYANATES | BIORESEARCH, INC. (US) | 1989-05-09 | — | — | US | disclosed |
| WO-1989000589-A1 | METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES | BIORESEARCH, INC. (US) | 1989-01-26 | — | — | WO | disclosed |