SCHEMBL40349

SCHEMBL40349

COC(=O)c1cccc(N=C=O)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.51
CYP4A11 Q02928 2/20 0.51
LOXL2 Q9Y4K0 1/20 0.49
TSHR P16473 1/20 0.48
RAB9A P51151 4/20 0.47
MAPT P10636 2/20 0.47
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
POLB P06746 1/20 0.46
ALDH1A1 P00352 1/20 0.45
ERN1 O75460 1/20 0.44
HCRTR1 O43613 1/20 0.44
HCRTR2 O43614 1/20 0.44
NPC1 O15118 2/20 0.44
PRSS1 P07477 1/20 0.44
ACR P10323 1/20 0.44
GRIN2D O15399 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15961477 0.87 CYP4F2 (0.39) CYP4F2CYP4A11LOXL2TSHRRAB9A
SCHEMBL19351446 0.86 TSHR (0.62) CYP4F2CYP4A11TSHRRAB9AMAPT
SCHEMBL69663 0.86 RAB9A (0.62) CYP4F2CYP4A11LOXL2TSHRRAB9A
SCHEMBL69664 0.86 RAB9A (0.62) CYP4F2CYP4A11LOXL2TSHRRAB9A
SCHEMBL29754225 0.85 ALDH1A1 (0.48) CYP4F2CYP4A11LOXL2TSHRRAB9A
SCHEMBL1421363 0.85 ALDH1A1 (0.48) CYP4F2CYP4A11LOXL2TSHRRAB9A
SCHEMBL7525356 0.84 NEK1 (0.42) CYP4F2CYP4A11TSHRRAB9AMAPT
SCHEMBL445504 0.83 CYP4F2 (0.50) CYP4F2CYP4A11TSHRRAB9AMAPT
SCHEMBL30427003 0.83 CYP4F2 (0.50) CYP4F2CYP4A11TSHRRAB9AMAPT
SCHEMBL5502036 0.83 SLC7A5 (0.46) CYP4F2CYP4A11TSHRRAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 286 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4713378-A1 ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS Covestro Deutschland AG (DE) 2026-03-25 EP disclosed
EP-3774961-B1 ADDUCTS OF AMINE CATALYSTS FOR PRODUCING ISOCYANURATE POLYMERS COVESTRO DEUTSCHLAND AG (DE) 2025-01-15 EP disclosed
WO-2024236000-A1 ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS COVESTRO DEUTSCHLAND AG (DE) 2024-11-21 WO disclosed
EP-4464727-A1 ESTERIFIED ETHANOLAMINES FOR THE PREPARATION OF ISOCYANURATE POLYMERS Covestro Deutschland AG (DE) 2024-11-20 EP disclosed
US-20240150515-A1 Low Viscosity Catalyst Compositions for Producing Isocyanurate Polymers COVESTRO DEUTSCHLAND AG (DE) 2024-05-09 US disclosed
EP-4298140-A1 LOW VISCOSITY CATALYST COMPOSITIONS FOR PRODUCING ISOCYANURATE POLYMERS Covestro Deutschland AG (DE) 2024-01-03 EP disclosed
CN-116917364-A Low viscosity catalyst composition for producing isocyanurate polymers 科思创德国股份有限公司 2023-10-20 CN disclosed
CN-112020525-B Adducts of amine catalysts for preparing isocyanurate polymers 科思创知识产权两合公司 2023-05-16 CN disclosed
US-20220363809-A1 POLYMERIZABLE COMPOSITIONS FOR PREPARING POLYISOCYANURATE-BASED PLASTICS HAVING EXTENDED WORKLIFE COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2022-11-17 US disclosed
WO-2022179939-A1 LOW VISCOSITY CATALYST COMPOSITIONS FOR PRODUCING ISOCYANURATE POLYMERS COVESTRO DEUTSCHLAND AG (DE) 2022-09-01 WO disclosed
WO-1990006937-A1 DERIVATIVES OF TETRAPEPTIDES AS CCK AGONISTS ABBOTT LABORATORIES (US) 1990-06-28 WO disclosed
US-4863947-A PESTICIDES, INSECTICIDES ROHM AND HAAS (US) 1989-09-05 US disclosed
US-4663341-A Insecticidal n-aryl-3-aryl-4,5-dihydro-1h-pyrazole-1-carboxamides ROHM AND HAAS COMPANY (US) 1987-05-05 US disclosed
CN-85101497-A Process for the preparation of N-aryl-3-aryl-4, 5-dihydro-1H-pyrazole-1-carboxamides 1986-07-16 CN disclosed
EP-0153127-A2 N-aryl-3-aryl-4,5-dihydro-1H-pyrazole-1-carboxamides, processes for their production, insecticidal compositions containing them and methods for combatting insects ROHM AND HAAS COMPANY (US) 1985-08-28 EP disclosed
EP-0000602-B1 PROCESS FOR THE PREPARATION OF ISOCYANATES FROM FORMAMIDES AKZO N.V. (NL) 1981-07-22 EP disclosed
US-4207251-A Catalytic oxidation of formamides to form isocyanates AKZONA INCORPORATED (US) 1980-06-10 US disclosed
US-4174398-A Combating fungi with 1-alkyl-1-(1,3,4-thiadiazol-2-yl)-3-phenyl-ureas BAYER AKTIENGESELLSCHAFT (DE) 1979-11-13 US disclosed
EP-0000602-A1 Process for the preparation of isocyanates from formamides AKZO N.V. (NL) 1979-02-07 EP disclosed
US-4096334-A Process for the manufacture of carbodiimides HOECHST AKTIENGESELLSCHAFT (DT) 1978-06-20 US disclosed