Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949910 | 0.93 | THRB (0.41) | MEN1KMT2ATHRBMAPTTSHR | |
| SCHEMBL5528349 | 0.93 | THRB (0.41) | MEN1KMT2ATHRBMAPTTSHR | |
| SCHEMBL2535258 | 0.91 | MEN1 (0.44) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL29519318 | 0.91 | MEN1 (0.44) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL29519084 | 0.91 | MEN1 (0.44) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL29519177 | 0.91 | MEN1 (0.44) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL7530528 | 0.91 | MEN1 (0.44) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL24496157 | 0.91 | ALDH1A1 (0.41) | MEN1KMT2ATHRBMAPTTSHR | |
| SCHEMBL50311 | 0.89 | MEN1 (0.41) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL5413785 | 0.89 | ALDH1A1 (0.40) | MEN1KMT2ATHRBMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5280078-A | Homopolymers and copolymers of acrylamide N-substituted acrylamide or N-substituted methacrylamide solid state cross-linked with polyamines or polyols | GREGOR HARRY P (US) | 1994-01-18 | — | — | US | disclosed |
| EP-0240586-B1 | POST-CROSS-LINKED POLYMERIC GELS | Gregor, Harry P. (US) | 1993-01-20 | — | — | EP | disclosed |
| US-4705753-A | Biologically active acrylonitrile-based copolymeric membrane | GREGOR HARRY P (US) | 1987-11-10 | — | — | US | disclosed |