Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | ATM | Q13315 | 3/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alpha-Cypermethrin SCHEMBL5074418 | 1.00 | TDP1 (1.00) | TDP1ALDH1A1LMNAATMADRA2A | |
| Beta-Cypermethrin SCHEMBL5934059 | 1.00 | TDP1 (1.00) | TDP1ALDH1A1LMNAATMADRA2A | |
| Alpha-Cypermethrin SCHEMBL1088177 | 1.00 | TDP1 (1.00) | TDP1ALDH1A1LMNAATMADRA2A | |
| Alpha-Cypermethrin SCHEMBL120157 | 1.00 | TDP1 (1.00) | TDP1ALDH1A1LMNAATMADRA2A | |
| Alpha-Cypermethrin SCHEMBL942530 | 1.00 | TDP1 (1.00) | TDP1ALDH1A1LMNAATMADRA2A | |
| Alpha-Cypermethrin SCHEMBL4338885 | 1.00 | TDP1 (1.00) | TDP1ALDH1A1LMNAATMADRA2A | |
| Alpha-Cypermethrin SCHEMBL1088295 | 1.00 | TDP1 (1.00) | TDP1ALDH1A1LMNAATMADRA2A | |
| Alpha-Cypermethrin SCHEMBL1086935 | 1.00 | TDP1 (1.00) | TDP1ALDH1A1LMNAATMADRA2A | |
| Alpha-Cypermethrin SCHEMBL11344290 | 1.00 | TDP1 (1.00) | TDP1ALDH1A1LMNAATMADRA2A | |
| Alpha-Cypermethrin SCHEMBL1087559 | 1.00 | TDP1 (1.00) | TDP1ALDH1A1LMNAATMADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110002877-A1 | PTEN Inhibitors Treat Neutropenia-Associated Pneumonia | CHILDREN'S MEDICAL CENTER CORPORATION | 2011-01-06 | — | — | US | claimed |
| EP-1889028-A1 | METHOD FOR DETERMINING PESTICIDE RESIDUES IN SOIL OR PLANT MATERIAL | BASF AKTIENGESELLSCHAFT (DE) | 2008-02-20 | — | — | EP | claimed |
| WO-2006125644-A1 | METHOD FOR DETERMINING PESTICIDE RESIDUES IN SOIL OR PLANT MATERIAL | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-30 | — | — | WO | claimed |
| US-4668511-A | PHOTOSTABILITY, PYRETHRINOID, BACULOVIRUS | INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (FR) | 1987-05-26 | — | — | US | claimed |
| US-20190022084-A1 | PROMOTING AXON RENEGERATION IN THE ADULT CNS THROUGH CONTROL OF PROTEIN TRANSLATION | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2019-01-24 | — | — | US | disclosed |
| US-10117866-B2 | Promoting axon regeneration in the adult CNS through control of protein translation | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2018-11-06 | — | — | US | disclosed |
| EP-2502623-B1 | Promoting Axon Regeneration in the Adult CNS through Control of Protein Translation | CHILDRENS MEDICAL CENTER (US) | 2016-04-06 | — | — | EP | disclosed |
| US-20140213609-A1 | PROMOTING AXON RENEGERATION IN THE ADULT CNS THROUGH CONTROL OF PROTEIN TRANSLATION | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2014-07-31 | — | — | US | disclosed |
| US-8728756-B2 | Promoting axon regeneration in the adult CNS through control of protein translation | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2014-05-20 | — | — | US | disclosed |
| US-20130123228-A1 | PROMOTING AXON REGENERATION IN THE ADULT CNS THROUGH CONTROL OF PROTEIN TRANSLATION | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2013-05-16 | — | — | US | disclosed |
| US-8367352-B2 | Promoting axon regeneration in the adult CNS through control of protein translation | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2013-02-05 | — | — | US | disclosed |
| US-20130012578-A1 | Novel Formulations of Bifenthrin and Enriched Cypermethrin | FMC CORPORATION (US) | 2013-01-10 | — | — | US | disclosed |
| WO-2006125647-A1 | METHOD FOR DETERMINING RESIDUES IN PLASTICS | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-30 | — | — | WO | disclosed |
| WO-2006125644-A1 | METHOD FOR DETERMINING PESTICIDE RESIDUES IN SOIL OR PLANT MATERIAL | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-30 | — | — | WO | disclosed |
| WO-2000002453-A1 | PESTICIDAL COMPOSITION COMPRISING EMAMECTIN | NOVARTIS AG (CH) | 2000-01-20 | — | — | WO | disclosed |
| EP-0900024-A1 | PESTICIDAL COMPOSITIONS | Novartis AG (CH) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997040692-A1 | PESTICIDAL COMPOSITIONS | NOVARTIS AG (CH) | 1997-11-06 | — | — | WO | disclosed |
| US-5028731-A | Reaction Of An Alpha-Hydroxyphenoxyphenylacetonitrile With A Cyclopropanecarbonyl Chloride Without Use Of An Acid Acceptor To Enhance Production Of Insecticidally Active Isomers | FMC CORPORATION (US) | 1991-07-02 | — | — | US | disclosed |
| US-4308279-A | STEREOISOMERS | FMC CORPORATION (US) | 1981-12-29 | — | — | US | disclosed |
| US-4181735-A | A-CYANO-3-PHENOXY-BENZYL 2,2-DIMETHYL-3-(2',2'-DIBROMO- OR DICHLORO-VINYL)-CYCLOPROPANE-1-CARBOXYLATE | ROUSSEL UCLAF (FR) | 1980-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110002877-A1 | PTEN Inhibitors Treat Neutropenia-Associated Pneumonia | CSF3R, CSF1R, ATM | TDP1 1904/4885ALDH1A1 4692/4885LMNA 3952/4885 |
| US-20130123228-A1 | PROMOTING AXON REGENERATION IN THE ADULT CNS THROUGH CONTROL OF PROTEIN TRANSLATION | GAP43, BDNF, DCX | TDP1 2251/4885ALDH1A1 3775/4885LMNA 2659/4885 |
| US-20190022084-A1 | PROMOTING AXON RENEGERATION IN THE ADULT CNS THROUGH CONTROL OF PROTEIN TRANSLATION | GAP43, BDNF, PMP22 | TDP1 2350/4885ALDH1A1 4552/4885LMNA 1777/4885 |
| US-20140213609-A1 | PROMOTING AXON RENEGERATION IN THE ADULT CNS THROUGH CONTROL OF PROTEIN TRANSLATION | GAP43, DCX, BDNF | TDP1 2593/4885ALDH1A1 3981/4885LMNA 2349/4885 |
| US-10117866-B2 | Promoting axon regeneration in the adult CNS through control of protein translation | GAP43, BDNF, DCX | TDP1 2251/4885ALDH1A1 3775/4885LMNA 2659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.