Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | ATM | Q13315 | 3/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alpha-Cypermethrin SCHEMBL5074418 | 1.00 | TDP1 (1.00) | TDP1ALDH1A1LMNAATMADRA2A | |
| Beta-Cypermethrin SCHEMBL5934059 | 1.00 | TDP1 (1.00) | TDP1ALDH1A1LMNAATMADRA2A | |
| Alpha-Cypermethrin SCHEMBL942094 | 1.00 | TDP1 (1.00) | TDP1ALDH1A1LMNAATMADRA2A | |
| Alpha-Cypermethrin SCHEMBL1088177 | 1.00 | TDP1 (1.00) | TDP1ALDH1A1LMNAATMADRA2A | |
| Alpha-Cypermethrin SCHEMBL120157 | 1.00 | TDP1 (1.00) | TDP1ALDH1A1LMNAATMADRA2A | |
| Alpha-Cypermethrin SCHEMBL4338885 | 1.00 | TDP1 (1.00) | TDP1ALDH1A1LMNAATMADRA2A | |
| Alpha-Cypermethrin SCHEMBL1088295 | 1.00 | TDP1 (1.00) | TDP1ALDH1A1LMNAATMADRA2A | |
| Alpha-Cypermethrin SCHEMBL1086935 | 1.00 | TDP1 (1.00) | TDP1ALDH1A1LMNAATMADRA2A | |
| Alpha-Cypermethrin SCHEMBL11344290 | 1.00 | TDP1 (1.00) | TDP1ALDH1A1LMNAATMADRA2A | |
| Alpha-Cypermethrin SCHEMBL1087559 | 1.00 | TDP1 (1.00) | TDP1ALDH1A1LMNAATMADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110002877-A1 | PTEN Inhibitors Treat Neutropenia-Associated Pneumonia | CHILDREN'S MEDICAL CENTER CORPORATION | 2011-01-06 | — | — | US | claimed |
| US-10941194-B2 | Methods of diagnosing and treating autism spectrum disorders | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-03-09 | — | — | US | disclosed |
| US-10117866-B2 | Promoting axon regeneration in the adult CNS through control of protein translation | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2018-11-06 | — | — | US | disclosed |
| US-20180002410-A1 | METHODS OF DIAGNOSING AND TREATING AUTISM SPECTRUM DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-01-04 | — | — | US | disclosed |
| US-9492408-B2 | Protection from chemical-induced acute lung injury | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2016-11-15 | — | — | US | disclosed |
| US-9492408-B2 | Protection from chemical-induced acute lung injury | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2016-11-15 | — | — | US | disclosed |
| US-20150119468-A1 | PROTECTION FROM CHEMICAL-INDUCED ACUTE LUNG INJURY | University of Pittsburgh–of the Commonwealth System of Higher Education (US) | 2015-04-30 | — | — | US | disclosed |
| US-20150119468-A1 | PROTECTION FROM CHEMICAL-INDUCED ACUTE LUNG INJURY | University of Pittsburgh–of the Commonwealth System of Higher Education (US) | 2015-04-30 | — | — | US | disclosed |
| US-20140213609-A1 | PROMOTING AXON RENEGERATION IN THE ADULT CNS THROUGH CONTROL OF PROTEIN TRANSLATION | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2014-07-31 | — | — | US | disclosed |
| US-20110002877-A1 | PTEN Inhibitors Treat Neutropenia-Associated Pneumonia | CHILDREN'S MEDICAL CENTER CORPORATION | 2011-01-06 | — | — | US | disclosed |
| US-20070203098-A1 | Pten Inhibitors | SEMAFORE PHARMACEUTICALS, INC. (US) | 2007-08-30 | — | — | US | disclosed |
| US-20070203098-A1 | Pten Inhibitors | SEMAFORE PHARMACEUTICALS, INC. (US) | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110002877-A1 | PTEN Inhibitors Treat Neutropenia-Associated Pneumonia | CSF3R, CSF1R, ATM | TDP1 1904/4885ALDH1A1 4692/4885LMNA 3952/4885 |
| US-20150119468-A1 | PROTECTION FROM CHEMICAL-INDUCED ACUTE LUNG INJURY | DUSP10, CASP10, PHF20 | TDP1 1912/4885ALDH1A1 1433/4885LMNA 2543/4885 |
| US-20070203098-A1 | Pten Inhibitors | PTEN, MTMR1, PTPRJ | TDP1 258/4885ALDH1A1 2982/4885LMNA 2778/4885 |
| US-20140213609-A1 | PROMOTING AXON RENEGERATION IN THE ADULT CNS THROUGH CONTROL OF PROTEIN TRANSLATION | GAP43, DCX, BDNF | TDP1 2593/4885ALDH1A1 3981/4885LMNA 2349/4885 |
| US-10117866-B2 | Promoting axon regeneration in the adult CNS through control of protein translation | GAP43, BDNF, DCX | TDP1 2251/4885ALDH1A1 3775/4885LMNA 2659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.