Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.59 |
| ▸ | ESR1 | P03372 | 2/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | TACR2 | P21452 | 2/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SHBG | P04278 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560359 | 0.97 | PTGS2 (0.70) | PTGS2CYP3A4GPR84ESR1ADRA2A | |
| SCHEMBL7628223 | 0.97 | PTGS2 (0.70) | PTGS2CYP3A4GPR84ESR1ADRA2A | |
| SCHEMBL9122379 | 0.97 | PTGS2 (0.70) | PTGS2CYP3A4GPR84ESR1ADRA2A | |
| SCHEMBL2871788 | 0.94 | PTGS2 (0.68) | PTGS2CYP3A4GPR84ESR1ADRA2A | |
| Ethylene SCHEMBL28058312 | 0.92 | PTGS2 (0.64) | PTGS2CYP3A4GPR84ESR1ADRA2A | |
| SCHEMBL1187883 | 0.90 | PTGS2 (0.61) | PTGS2CYP3A4GPR84ESR1ADRA2A | |
| SCHEMBL1187238 | 0.90 | PTGS2 (0.61) | PTGS2CYP3A4GPR84ESR1ADRA2A | |
| SCHEMBL1188265 | 0.90 | PTGS2 (0.61) | PTGS2CYP3A4GPR84ESR1ADRA2A | |
| SCHEMBL1188932 | 0.90 | PTGS2 (0.61) | PTGS2CYP3A4GPR84ESR1ADRA2A | |
| SCHEMBL1186937 | 0.90 | PTGS2 (0.61) | PTGS2CYP3A4GPR84ESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5321105-A | Polymerization process using a bimodal silica gel as a catalyst support | QUANTUM CHEMICAL CORPORATION (US) | 1994-06-14 | — | — | US | claimed |
| US-5231066-A | Bimodal silica gel, its preparation and use as a catalyst support | QUANTUM CHEMICAL CORPORATION (US) | 1993-07-27 | — | — | US | claimed |
| US-5321105-A | Polymerization process using a bimodal silica gel as a catalyst support | QUANTUM CHEMICAL CORPORATION (US) | 1994-06-14 | — | — | US | disclosed |
| US-5231066-A | Bimodal silica gel, its preparation and use as a catalyst support | QUANTUM CHEMICAL CORPORATION (US) | 1993-07-27 | — | — | US | disclosed |
| US-4681866-A | TREATED SILICA SUPPORT AND ZEROVALENT CHROMIUM COMPOUND | PHILLIPS PETROLEUM COMPANY (US) | 1987-07-21 | — | — | US | disclosed |
| US-4619980-A | TREATED SILICA SUPPORT AND ZEROVALENT CHROMIUM COMPOUND | PHILLIPS PETROLEUM COMPANY (US) | 1986-10-28 | — | — | US | disclosed |
| US-4444968-A | SENSITIVITY TO HYDROGEN | PHILLIPS PETROLEUM COMPANY (US) | 1984-04-24 | — | — | US | disclosed |
| US-4364841-A | POLYMERIZATION CATALYST FOR ALPHA-OLEFINS | PHILLIPS PETROLEUM COMPANY (US) | 1982-12-21 | — | — | US | disclosed |
| EP-0055865-A2 | Catalyst, method of making and use of same for polymerizing olefins | PHILLIPS PETROLEUM COMPANY (US) | 1982-07-14 | — | — | EP | disclosed |
| US-4188471-A | DIBENZENE CHROMIUM OR DICUMENE CHROMIUM ON SILICA-TITANIA SUPPORT | PHILLIPS PETROLEUM COMPANY (US) | 1980-02-12 | — | — | US | disclosed |
| US-4001196-A | Reactivation of organochromium olefin polymerization catalyst in presence of oxygen | PHILLIPS PETROLEUM COMPANY (US) | 1977-01-04 | — | — | US | disclosed |
| US-3976632-A | Reactivation of organochromium olefin polymerization catalyst in presence of oxygen | PHILLIPS PETROLEUM COMPANY (US) | 1976-08-24 | — | — | US | disclosed |