Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | GLB1 | P16278 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | CTRC | Q99895 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9422003 | 1.00 | CYP1B1 (0.50) | CYP1B1CYP1A1KMT2AMEN1GAA | |
| SCHEMBL11577483 | 0.89 | CYP1B1 (0.41) | CYP1B1CYP1A1KMT2AMEN1GAA | |
| SCHEMBL11577481 | 0.89 | CYP1B1 (0.41) | CYP1B1CYP1A1KMT2AMEN1GAA | |
| SCHEMBL11577477 | 0.89 | CYP1B1 (0.41) | CYP1B1CYP1A1KMT2AMEN1GAA | |
| SCHEMBL11884061 | 0.84 | CYP1B1 (0.58) | CYP1B1KMT2AMEN1GAARAB9A | |
| SCHEMBL11884055 | 0.84 | CYP1B1 (0.58) | CYP1B1KMT2AMEN1GAARAB9A | |
| SCHEMBL9422039 | 0.81 | ALDH1A1 (0.53) | CYP1B1CYP1A1KMT2AMEN1GAA | |
| SCHEMBL3880767 | 0.81 | ALDH1A1 (0.53) | CYP1B1CYP1A1KMT2AMEN1GAA | |
| SCHEMBL9422010 | 0.81 | KMT2A (0.40) | CYP1B1KMT2AMEN1GAARAB9A | |
| SCHEMBL9422018 | 0.81 | KMT2A (0.40) | CYP1B1KMT2AMEN1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340804-A | In vertebrate animals | ELI LILLY AND COMPANY (US) | 1994-08-23 | — | — | US | disclosed |