SCHEMBL9422307

SCHEMBL9422307

O=P(c1ccccc1)(c1ccccc1)c1cccc2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.47
KDM4E B2RXH2 2/20 0.47
LMNA P02545 2/20 0.47
NPSR1 Q6W5P4 2/20 0.46
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
ALDH1A1 P00352 2/20 0.42
HTT P42858 1/20 0.42
TOP1 P11387 1/20 0.41
NR4A1 P22736 1/20 0.41
NR4A2 P43354 1/20 0.41
NR4A3 Q92570 1/20 0.41
ACP3 P15309 1/20 0.40
PTK2B Q14289 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TDP1 Q9NUW8 2/20 0.39
CYP2A6 P11509 1/20 0.39
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29644308 1.00 POLB (0.47) POLBKDM4ELMNANPSR1MEN1
SCHEMBL14339295 0.98 LMNA (0.46) POLBKDM4ELMNANPSR1MEN1
SCHEMBL14339284 0.96 LMNA (0.45) POLBKDM4ELMNANPSR1MEN1
SCHEMBL14339278 0.96 LMNA (0.45) POLBKDM4ELMNANPSR1MEN1
SCHEMBL14339276 0.96 LMNA (0.45) POLBKDM4ELMNANPSR1MEN1
SCHEMBL31212642 0.96 KDM4E (0.47) POLBKDM4ELMNANPSR1MEN1
SCHEMBL11451532 0.96 KDM4E (0.47) POLBKDM4ELMNANPSR1MEN1
SCHEMBL14339296 0.94 POLB (0.44) POLBKDM4ELMNANPSR1MEN1
SCHEMBL14339268 0.94 POLB (0.44) POLBKDM4ELMNANPSR1MEN1
SCHEMBL5760742 0.93 TOP1 (0.43) POLBKDM4ELMNANPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114685562-A Diphenyl naphthyl phosphine oxide derivative with asymmetric structure, organic electron transport material, preparation and application thereof 华南理工大学 2022-07-01 CN claimed
CN-114573636-A P, N chiral quinoxaline compound and preparation method and application thereof 中国科学院兰州化学物理研究所 2022-06-03 CN claimed
JP-6256367-A None JP disclosed
WO-2025057775-A1 MATERIAL FOR PHOTOELECTRIC CONVERSION ELEMENT FOR IMAGING ELEMENT, AND IMAGING ELEMENT 東ソー株式会社 2025-03-20 WO disclosed
CN-114685562-A Diphenyl naphthyl phosphine oxide derivative with asymmetric structure, organic electron transport material, preparation and application thereof 华南理工大学 2022-07-01 CN disclosed
CN-114685562-A Diphenyl naphthyl phosphine oxide derivative with asymmetric structure, organic electron transport material, preparation and application thereof 华南理工大学 2022-07-01 CN disclosed
CN-114573636-A P, N chiral quinoxaline compound and preparation method and application thereof 中国科学院兰州化学物理研究所 2022-06-03 CN disclosed
CN-113457746-A Catalyst and preparation method and application thereof 南方科技大学 2021-10-01 CN disclosed
JP-H06256367-A NEW METHOD FOR PRODUCTING PHOSPHINE COMPOUND SUMITOMO SEIKA CHEM CO LTD 1994-09-13 JP disclosed