SCHEMBL14339276

SCHEMBL14339276

O=P(c1ccc(P(=O)(c2ccccc2)c2cccc3ccccc23)cc1)(c1ccc(P(=O)(c2ccccc2)c2cccc3ccccc23)cc1)c1ccc(P(=O)(c2ccccc2)c2cccc3ccccc23)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.45
POLB P06746 2/20 0.45
KDM4E B2RXH2 2/20 0.45
NPSR1 Q6W5P4 2/20 0.44
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 2/20 0.40
HTT P42858 1/20 0.40
TOP1 P11387 1/20 0.39
NR4A1 P22736 1/20 0.38
NR4A2 P43354 1/20 0.38
NR4A3 Q92570 1/20 0.38
ACP3 P15309 2/20 0.38
PTK2B Q14289 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
HPGD P15428 1/20 0.37
NPC1 O15118 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14339284 1.00 LMNA (0.45) LMNAPOLBKDM4ENPSR1MEN1
SCHEMBL14339278 1.00 LMNA (0.45) LMNAPOLBKDM4ENPSR1MEN1
SCHEMBL14339295 0.98 LMNA (0.46) LMNAPOLBKDM4ENPSR1MEN1
SCHEMBL5760742 0.96 TOP1 (0.43) LMNAPOLBKDM4ENPSR1MEN1
SCHEMBL14339281 0.96 LMNA (0.45) LMNAPOLBKDM4ENPSR1MEN1
SCHEMBL9422307 0.96 POLB (0.47) LMNAPOLBKDM4ENPSR1MEN1
SCHEMBL29644308 0.96 POLB (0.47) LMNAPOLBKDM4ENPSR1MEN1
SCHEMBL17451881 0.95 TOP1 (0.42) LMNAPOLBKDM4ENPSR1MEN1
SCHEMBL5437709 0.92 LMNA (0.47) LMNAPOLBKDM4EALDH1A1NR4A1
SCHEMBL11451532 0.92 KDM4E (0.47) LMNAPOLBKDM4ENPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9406910-B2 Organic electroluminescent element and manufacturing method thereof, and phosphorus-containing organic compound and manufacturing method thereof DAIDEN CO., LTD (JP) 2016-08-02 US disclosed
US-9406910-B2 Organic electroluminescent element and manufacturing method thereof, and phosphorus-containing organic compound and manufacturing method thereof DAIDEN CO., LTD (JP) 2016-08-02 US disclosed
US-20130295706-A1 Organic Electroluminescent Element and Manufacturing Method Thereof, and Phosphorus-Containing Organic Compound and Manufacturing Method Thereof KYUSHU ELECTRIC POWER CO., INC. (JP) 2013-11-07 US disclosed
US-20130295706-A1 Organic Electroluminescent Element and Manufacturing Method Thereof, and Phosphorus-Containing Organic Compound and Manufacturing Method Thereof KYUSHU ELECTRIC POWER CO., INC. (JP) 2013-11-07 US disclosed
US-20070290605-A1 Organic Electroluminescent Element and Manufacturing Method Thereof, and Phosphorus-Containing Organic Compound and Manufacturing Method Thereof KYUSHU ELECTRIC POWER CO., INC. (JP) 2007-12-20 US disclosed
US-20070290605-A1 Organic Electroluminescent Element and Manufacturing Method Thereof, and Phosphorus-Containing Organic Compound and Manufacturing Method Thereof KYUSHU ELECTRIC POWER CO., INC. (JP) 2007-12-20 US disclosed
US-20070228356-A1 ORGANIC-INORGANIC COMPOSITE SEMICONDUCTOR MATERIAL, LIQUID MATERIAL, ORGANIC LIGHT EMITTING ELEMENT, METHOD OF MANUFACTURING ORGANIC LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE AND ELECTRONIC APPARATUS SEIKO EPSON CORPORATION (JP) 2007-10-04 US disclosed
US-20070228356-A1 ORGANIC-INORGANIC COMPOSITE SEMICONDUCTOR MATERIAL, LIQUID MATERIAL, ORGANIC LIGHT EMITTING ELEMENT, METHOD OF MANUFACTURING ORGANIC LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE AND ELECTRONIC APPARATUS SEIKO EPSON CORPORATION (JP) 2007-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070290605-A1 Organic Electroluminescent Element and Manufacturing Method Thereof, and Phosphorus-Containing Organic Compound and Manufacturing Method Thereof SLCO4C1, SLC10A6, SLC19A2 LMNA 2279/4885POLB 1106/4885KDM4E 1932/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.