Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3767157 | 0.84 | LMNA (0.47) | MAOAMAOBLMNASMN1; SMN2TSHR | |
| SCHEMBL10052139 | 0.81 | MAOA (0.45) | MAOAMAOBLMNASMN1; SMN2HIF1A | |
| SCHEMBL645262 | 0.78 | TSHR (0.48) | MAOAMAOBSMN1; SMN2HIF1ATSHR | |
| SCHEMBL7721376 | 0.75 | MAOA (0.51) | MAOAMAOBLMNASMN1; SMN2HIF1A | |
| SCHEMBL3023046 | 0.73 | SMN1; SMN2 (0.43) | MAOAMAOBLMNASMN1; SMN2HIF1A | |
| SCHEMBL31473075 | 0.72 | SMN1; SMN2 (0.56) | MAOAMAOBLMNASMN1; SMN2TSHR | |
| SCHEMBL9126809 | 0.72 | TSHR (0.42) | LMNASMN1; SMN2TSHRALDH1A1MAPT | |
| SCHEMBL11132592 | 0.72 | ESR2 (0.43) | MAOAMAOBSMN1; SMN2HIF1ATSHR | |
| SCHEMBL4456223 | 0.72 | SMN1; SMN2 (0.56) | MAOAMAOBLMNASMN1; SMN2TSHR | |
| SCHEMBL4091682 | 0.72 | LMNA (0.48) | MAOAMAOBLMNASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5376150-A | Use of pyridine dyes in the textile sector, dye mixtures with pyridine dyes, and triazolopyridine dyes having a thienyl radical | BASF AKTIENGESELLSCHAFT (DE) | 1994-12-27 | — | — | US | disclosed |