Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 10/20 | 0.86 |
| ▸ | AGTR2 | P50052 | 10/20 | 0.86 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9200811 | 0.92 | AGTR1 (1.00) | AGTR1AGTR2PPARG | |
| SCHEMBL9125532 | 0.86 | AGTR1 (0.80) | AGTR1AGTR2PPARG | |
| SCHEMBL7671655 | 0.85 | AGTR1 (0.83) | AGTR1AGTR2PPARG | |
| SCHEMBL9124594 | 0.85 | AGTR1 (0.78) | AGTR1AGTR2PPARG | |
| SCHEMBL9531448 | 0.84 | AGTR1 (0.61) | AGTR1AGTR2PPARG | |
| SCHEMBL10430040 | 0.82 | AGTR1 (0.80) | AGTR1AGTR2PPARG | |
| SCHEMBL9200654 | 0.82 | AGTR1 (1.00) | AGTR1AGTR2PPARG | |
| SCHEMBL9197947 | 0.82 | AGTR1 (1.00) | AGTR1AGTR2PPARG | |
| SCHEMBL9123025 | 0.81 | AGTR1 (1.00) | AGTR1AGTR2PPARG | |
| SCHEMBL8396814 | 0.81 | AGTR1 (0.79) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294631-A | Substituted benzimidazoles useful as angiotension II receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1994-03-15 | — | — | US | claimed |
| EP-0525129-A4 | SUBSTITUTED BENZIMIDAZOLES | — | 1993-03-24 | — | — | EP | claimed |
| EP-0525129-A1 | SUBSTITUTED BENZIMIDAZOLES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-02-03 | — | — | EP | claimed |
| WO-1991016313-A1 | SUBSTITUTED BENZIMIDAZOLES | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-31 | — | — | WO | claimed |