Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.57 |
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16104933 | 0.76 | TDP1 (0.55) | NPC1RAB9ALMNAHPGDALDH1A1 | |
| SCHEMBL7469469 | 0.76 | NPC1 (0.58) | NPC1RAB9ALMNAHPGDALDH1A1 | |
| SCHEMBL6267922 | 0.76 | HPGD (0.62) | NPC1RAB9ALMNAHPGDALDH1A1 | |
| SCHEMBL3653009 | 0.76 | RAB9A (0.50) | NPC1RAB9ALMNAHPGDALDH1A1 | |
| SCHEMBL14799462 | 0.75 | NPC1 (0.71) | NPC1RAB9ALMNAHPGDALDH1A1 | |
| SCHEMBL1433300 | 0.74 | NPC1 (0.60) | NPC1RAB9ALMNAHPGDALDH1A1 | |
| SCHEMBL10401993 | 0.74 | FFAR1 (0.54) | NPC1RAB9ALMNAHPGDALDH1A1 | |
| SCHEMBL7757826 | 0.73 | NPC1 (0.58) | NPC1RAB9ALMNAHPGDALDH1A1 | |
| SCHEMBL6830087 | 0.73 | NPC1 (0.58) | NPC1RAB9ALMNAHPGDALDH1A1 | |
| SCHEMBL422787 | 0.73 | RAB9A (0.62) | NPC1RAB9ALMNAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354549-A | Iodinated esters | NYCOMED IMAGING AS (NO) | 1994-10-11 | — | — | US | disclosed |
| EP-0300828-B1 | IODINATED ESTERS | NYCOMED AS (NO) | 1992-03-18 | — | — | EP | disclosed |
| EP-0300828-A1 | Iodinated esters | NYCOMED AS (NO) | 1989-01-25 | — | — | EP | disclosed |