Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.58 |
| ▸ | RAB9A | P51151 | 9/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.58 |
| ▸ | PTGES | O14684 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203582 | 0.80 | NPC1 (0.67) | NPC1RAB9AMAPTSMN1; SMN2HCRTR1 | |
| SCHEMBL9851957 | 0.77 | MAPT (0.49) | NPC1RAB9AMAPTSMN1; SMN2HCRTR1 | |
| SCHEMBL10350268 | 0.77 | ALDH1A1 (0.62) | NPC1RAB9AMAPTSMN1; SMN2HCRTR1 | |
| SCHEMBL9422931 | 0.76 | NPC1 (0.57) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL14214153 | 0.74 | NPC1 (0.58) | NPC1RAB9AMAPTSMN1; SMN2HCRTR1 | |
| SCHEMBL1355962 | 0.74 | CA1 (0.67) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL4765892 | 0.74 | — | — | |
| SCHEMBL14399049 | 0.73 | HPGD (0.59) | NPC1RAB9AMAPTSMN1; SMN2HCRTR1 | |
| SCHEMBL15572345 | 0.73 | FFAR1 (0.95) | NPC1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL711360 | 0.73 | RAB9A (0.75) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0867437-B1 | \"Method of preparing a thiophene-containing or furan -containing conjugated compound and precursor compound used therein\". | KONINKL PHILIPS ELECTRONICS NV (NL) | 2002-11-13 | — | — | EP | disclosed |
| US-6184540-B1 | SEMICONDUCTOR HAVING A LAYER OF A POLYTHIOPHENE DERIVED FROM A SOLUBLE PRECURSOR COMPOUND OF TETRAHYDROTHIOPHENE OR TETRAHYDROFURAN UNITS HAVING THERMALLY SEPARABLE ARYL- OR ALKYL-THIO SUBSTITUENTS, WHICH CAN BE PROCESSED FROM SOLUTION | U.S. PHILIPS CORPORATION | 2001-02-06 | — | — | US | disclosed |
| US-6124475-A | Method of preparing a thiophene-containing or furan-containing conjugated compound and precursor compound used therein | U.S. PHILIPS CORPORATION (US) | 2000-09-26 | — | — | US | disclosed |
| US-5919951-A | Method of preparing a thiophene-containing or furan-containing conjugated compound and precursor compound used therein | U.S. PHILIPS CORPORATION (US) | 1999-07-06 | — | — | US | disclosed |
| EP-0867437-A1 | \"Method of preparing a thiophene-containing or furan -containing conjugated compound and precursor compound used therein\". | Koninklijke Philips Electronics N.V. (NL) | 1998-09-30 | — | — | EP | disclosed |