Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9422961 | 1.00 | CCKBR (0.74) | CCKBRCCKAR | |
| SCHEMBL9423126 | 1.00 | CCKBR (0.74) | CCKBRCCKAR | |
| SCHEMBL9866235 | 0.89 | CCKBR (0.59) | CCKBRCCKAR | |
| SCHEMBL9866438 | 0.85 | CCKBR (1.00) | CCKBR | |
| SCHEMBL3888484 | 0.84 | KCNH2 (0.59) | CCKBR | |
| SCHEMBL14179828 | 0.83 | CCKBR (0.73) | CCKBR | |
| SCHEMBL9302350 | 0.83 | CCKBR (0.54) | CCKBR | |
| SCHEMBL9302341 | 0.83 | CCKBR (0.54) | CCKBR | |
| SCHEMBL9302348 | 0.83 | CCKBR (0.54) | CCKBR | |
| SCHEMBL8824746 | 0.82 | CCKBR (0.55) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5324726-A | Gastrointestinal disorders, synergistic compound for analgesic | MERCK & CO., INC. (US) | 1994-06-28 | — | — | US | disclosed |
| EP-0523845-A2 | New benzodiazepine analogs | MERCK & CO. INC. (US) | 1993-01-20 | — | — | EP | disclosed |
| EP-0490590-A1 | New benzodiazepine analogs | MERCK & CO. INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0434369-A1 | New benzodiazepine analogs | MERCK & CO. INC. (US) | 1991-06-26 | — | — | EP | disclosed |
| EP-0434364-A2 | Benzodiazepine analogs for treating panic syndrome and for directly inducing analgesia | MERCK & CO. INC. (US) | 1991-06-26 | — | — | EP | disclosed |
| EP-0434360-A1 | New benziodiazepine analogs | MERCK & CO. INC. (US) | 1991-06-26 | — | — | EP | disclosed |