Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F13A1 | P00488 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10339863 | 0.77 | HPGD (0.46) | F13A1TGM2HPGDNAPRTHSD17B10 | |
| SCHEMBL1413119 | 0.75 | F13A1 (0.46) | F13A1TGM2HPGDNAPRTHSD17B10 | |
| SCHEMBL11219965 | 0.75 | HPGD (0.45) | F13A1TGM2HPGDNAPRTHSD17B10 | |
| SCHEMBL8985174 | 0.71 | MEN1 (0.41) | F13A1TGM2KDM4EHPGDNAPRT | |
| SCHEMBL1404328 | 0.70 | TOP2A (0.42) | F13A1TGM2KDM4EHPGDNAPRT | |
| SCHEMBL9262914 | 0.70 | MEN1 (0.42) | F13A1TGM2HPGDTOP2ASLC22A12 | |
| SCHEMBL9271641 | 0.69 | POLB (0.41) | F13A1TGM2HPGDTOP2ASLC22A12 | |
| SCHEMBL9746506 | 0.68 | F13A1 (0.40) | F13A1TGM2KDM4EHPGDTOP2A | |
| SCHEMBL6865135 | 0.67 | F13A1 (0.38) | F13A1TGM2HPGDNAPRTHSD17B10 | |
| SCHEMBL1252939 | 0.65 | HPGD (0.44) | F13A1TGM2HPGDNAPRTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5278180-A | 4,5-bis(aryl) 4H-1,2,4-triazoles derivatives and analgesic use | ROUSSEL UCLAF (FR) | 1994-01-11 | — | — | US | disclosed |