SCHEMBL9746506

SCHEMBL9746506

Nc1ccc(OC2(N)C=CC(C(=O)Nc3ccccc3)C=C2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F13A1 P00488 3/20 0.40
TGM2 P21980 3/20 0.40
TOP2A P11388 1/20 0.38
SLC22A12 Q96S37 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
MAPT P10636 5/20 0.38
RAB9A P51151 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
LMNA P02545 1/20 0.37
GAA P10253 3/20 0.36
GFER P55789 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
KDM4E B2RXH2 1/20 0.36
GLA P06280 1/20 0.36
THRB P10828 1/20 0.36
BLM P54132 1/20 0.36
CASP6 P55212 1/20 0.36
HPGD P15428 1/20 0.35
CA12 O43570 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1413119 0.77 F13A1 (0.46) F13A1TGM2TOP2ASLC22A12HDAC6
SCHEMBL10339863 0.73 HPGD (0.46) F13A1TGM2TOP2ASLC22A12HDAC6
SCHEMBL11219965 0.71 HPGD (0.45) F13A1TGM2TOP2ASLC22A12HDAC6
SCHEMBL6865135 0.68 F13A1 (0.38) F13A1TGM2TOP2ASLC22A12HDAC6
SCHEMBL9423167 0.68 F13A1 (0.40) F13A1TGM2TOP2ASLC22A12HDAC6
SCHEMBL1627984 0.68 MAOA (0.36) MAPTRAB9AMEN1KMT2ALMNA
SCHEMBL8985174 0.67 MEN1 (0.41) F13A1TGM2TOP2ASLC22A12HDAC6
Ammonia Solution, Strong SCHEMBL10582921 0.67 MAOA (0.35) MAPTRAB9AMEN1KMT2ALMNA
SCHEMBL9200925 0.67 GAA (0.73) MAPTRAB9AMEN1KMT2ALMNA
SCHEMBL9746512 0.66 PRMT1 (0.36) MAPTRAB9AMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5112989-A Process for producing unsaturated mono and dicarboxylic acid imide compound MATSUSHITA ELECTRIC WORKS LTD. (JP) 1992-05-12 US disclosed
US-4830819-A Composition for fixing metal powder molding at sintering NITTO DENKO CORPORATION (JP) 1989-05-16 US disclosed
EP-0172274-B1 A METHOD FOR PREPARING POLYIMIDE PREPOLYMERS TORAY INDUSTRIES, INC. (JP) 1989-05-10 EP disclosed
EP-0160558-A2 Polyimide composition for fixing metallic sheets NITTO DENKO CORPORATION (JP) 1985-11-06 EP disclosed
US-4539392-A Method of preparing polyimide prepolymer from ethylenically unsaturated dicarboxylic acid compound TORAY INDUSTRIES, INC. (JP) 1985-09-03 US disclosed
US-4362863-A Process for production of polyimide resins NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1982-12-07 US disclosed