Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9423163 | 0.85 | TDP1 (0.36) | TDP1CTSBNOTUMALDH1A1NSD2 | |
| SCHEMBL9168174 | 0.78 | TDP1 (0.40) | TDP1CTSBNOTUMALDH1A1NSD2 | |
| SCHEMBL29576263 | 0.78 | TDP1 (0.40) | TDP1CTSBNOTUMALDH1A1NSD2 | |
| SCHEMBL9423041 | 0.78 | TDP1 (0.40) | TDP1CTSBNOTUMALDH1A1NSD2 | |
| SCHEMBL1807362 | 0.78 | TDP1 (0.52) | TDP1CTSBNOTUMALDH1A1NSD2 | |
| SCHEMBL4897613 | 0.77 | ALDH1A1 (0.38) | TDP1CTSBNOTUMALDH1A1NSD2 | |
| SCHEMBL44446 | 0.77 | ALDH1A1 (0.38) | TDP1CTSBNOTUMALDH1A1NSD2 | |
| SCHEMBL9423087 | 0.77 | TDP1 (0.36) | TDP1CTSBNOTUMALDH1A1NSD2 | |
| SCHEMBL6465173 | 0.77 | LMNA (0.47) | TDP1CTSBNOTUMALDH1A1NSD2 | |
| SCHEMBL9589477 | 0.77 | CYP4F2 (0.33) | TDP1CTSBNOTUMALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336663-A | 3-aryluracil derivatives and their use for weed control | CIBA-GEIGY CORPORATION (US) | 1994-08-09 | — | — | US | disclosed |
| EP-0542685-A1 | 3-Aryluracile derivatives and their use against weeds | CIBA-GEIGY AG (CH) | 1993-05-19 | — | — | EP | disclosed |