Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654844 | 0.87 | CYP1A2 (0.56) | CYP1A2CYP2C19CYP2C9HPGDPOLB | |
| SCHEMBL5858401 | 0.85 | CYP1A2 (0.55) | CYP1A2CYP2C19CYP2C9HPGDPOLB | |
| SCHEMBL4205954 | 0.85 | CYP1A2 (0.76) | CYP1A2CYP2C19CYP2C9HPGDPOLB | |
| SCHEMBL11647620 | 0.84 | CYP1A2 (0.58) | CYP1A2CYP2C19CYP2C9HPGDPOLB | |
| SCHEMBL9423229 | 0.82 | CYP1A2 (0.56) | CYP1A2CYP2C19CYP2C9HPGDPOLB | |
| SCHEMBL9424671 | 0.82 | CYP1A2 (0.58) | CYP1A2CYP2C19CYP2C9HPGDPOLB | |
| SCHEMBL11652356 | 0.80 | CYP1A2 (0.80) | CYP1A2CYP2C19CYP2C9HPGDPOLB | |
| SCHEMBL4199341 | 0.80 | ALDH1A1 (0.65) | CYP1A2CYP2C19CYP2C9HPGDPOLB | |
| SCHEMBL11650167 | 0.80 | CYP1A2 (0.53) | CYP1A2CYP2C19CYP2C9HPGDPOLB | |
| SCHEMBL4201730 | 0.79 | CYP1A2 (0.67) | CYP1A2CYP2C19CYP2C9HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5302714-A | Sapphyrins, derivatives and syntheses | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1994-04-12 | — | — | US | claimed |
| US-5302714-A | Sapphyrins, derivatives and syntheses | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1994-04-12 | — | — | US | disclosed |
| US-5159065-A | SAPPHYRINS, DERIVATIVES AND SYNTHESES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1992-10-27 | — | — | US | disclosed |