Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 3/20 | 0.39 |
| ▸ | DRD5 | P21918 | 3/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PMM2 | O15305 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9423391 | 0.88 | ALDH1A1 (0.49) | KDM4EGAAALDH1A1KMT2ATSHR | |
| SCHEMBL9423446 | 0.83 | TDP2 (0.50) | LMNAKMT2ACYP1A2 | |
| SCHEMBL9423386 | 0.78 | CYP19A1 (0.44) | KDM4ELMNARAB9AALDH1A1DRD1 | |
| SCHEMBL9423493 | 0.77 | ALDH1A1 (0.46) | KDM4EGAAALDH1A1KMT2ATSHR | |
| SCHEMBL9395502 | 0.73 | ALDH1A1 (0.49) | KDM4EGAAALDH1A1KMT2ATSHR | |
| SCHEMBL30162776 | 0.72 | DAO (0.57) | KDM4EGAALMNAKMT2A | |
| SCHEMBL2113080 | 0.72 | DAO (0.57) | KDM4EGAALMNAKMT2A | |
| SCHEMBL3968107 | 0.71 | ALDH1A1 (0.77) | ALDH1A1F10CCR2TSHR | |
| SCHEMBL28707236 | 0.70 | KDM4E (0.51) | KDM4EGAALMNARAB9AKMT2A | |
| SCHEMBL9423502 | 0.70 | ALDH1A1 (0.45) | KDM4EGAAALDH1A1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5318971-A | Also antihyperproliferative skin disease agents, e.g. psoriaisis; side effect reduction | SCHERING CORPORATION (US) | 1994-06-07 | — | — | US | disclosed |
| US-5064837-A | Antiallergens | SCHERING CORPORATION (US) | 1991-11-12 | — | — | US | disclosed |
| WO-1991007401-A1 | 3-SUBSTITUTED-1-(ARYL OR ARYLALKYL)-2(1H)-QUINOLINONES | SCHERING CORPORATION (US) | 1991-05-30 | — | — | WO | disclosed |