Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1755484 | 0.83 | ALDH1A1 (0.60) | ALDH1A1CYP3A4TDP1ALOX15TP53 | |
| SCHEMBL30802160 | 0.82 | ACHE (0.52) | ALDH1A1CYP3A4TDP1SMN1; SMN2ACHE | |
| SCHEMBL11890520 | 0.82 | ACHE (0.52) | ALDH1A1CYP3A4TDP1SMN1; SMN2ACHE | |
| SCHEMBL27808505 | 0.81 | ALDH1A1 (0.58) | ALDH1A1CYP3A4TDP1TP53SMN1; SMN2 | |
| SCHEMBL1188721 | 0.80 | ALDH1A1 (0.61) | ALDH1A1CYP3A4TDP1ALOX15TP53 | |
| SCHEMBL14217860 | 0.80 | ALDH1A1 (0.61) | ALDH1A1CYP3A4TDP1ALOX15TP53 | |
| SCHEMBL29601399 | 0.80 | HPGD (0.50) | ALDH1A1SMN1; SMN2ACHEGAAMEN1 | |
| SCHEMBL12772059 | 0.80 | HPGD (0.50) | ALDH1A1SMN1; SMN2ACHEGAAMEN1 | |
| SCHEMBL7281787 | 0.79 | ALDH1A1 (0.63) | ALDH1A1CYP3A4TDP1TP53SMN1; SMN2 | |
| SCHEMBL20597617 | 0.79 | SLC6A2 (0.41) | ALDH1A1CYP3A4TP53SMN1; SMN2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5308840-A | Antioxidants, antiallergens and antiinflammatory agents | GREEN CROSS CORPORATION (JP) | 1994-05-03 | — | — | US | disclosed |
| EP-0508334-A2 | Novel aminophenol derivatives and pharmaceutical compositions thereof | THE GREEN CROSS CORPORATION (JP) | 1992-10-14 | — | — | EP | disclosed |