Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9423717 | 0.93 | FFAR1 (0.48) | KMT2ALDHAFFAR1FFAR4HTT | |
| SCHEMBL2283360 | 0.81 | KMT2A (0.43) | KMT2ALDHAFFAR1FFAR4HTT | |
| SCHEMBL628528 | 0.80 | KMT2A (0.70) | KMT2ALDHAHTTLMNACYP1A2 | |
| SCHEMBL24306428 | 0.77 | NFE2L2 (0.46) | KMT2AHTTLMNAMAPK1ACHE | |
| SCHEMBL166380 | 0.75 | NFE2L2 (0.61) | FFAR1FFAR4MAPK1CYP1A2CYP3A4 | |
| SCHEMBL18472613 | 0.75 | NFE2L2 (0.61) | FFAR1FFAR4MAPK1CYP1A2CYP3A4 | |
| SCHEMBL8109358 | 0.75 | KMT2A (0.47) | KMT2AFFAR1FFAR4LMNACYP3A4 | |
| SCHEMBL9632874 | 0.74 | NFE2L2 (0.43) | CYP1A2CYP3A4CYP2C19CA12CA1 | |
| SCHEMBL2908009 | 0.74 | TSHR (0.62) | RAB9ACYP1A2CYP3A4CYP2C19TSHR | |
| SCHEMBL28299621 | 0.73 | NFE2L2 (0.59) | FFAR1FFAR4MAPK1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292740-A | Sulfonamides | HOFFMANN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |