Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CCR4 | P51679 | 1/20 | 0.35 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16026511 | 0.91 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL11747750 | 0.84 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2CHRNA7HSD17B10KDM4E | |
| SCHEMBL6308973 | 0.83 | ALDH1A1 (0.43) | ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL11742810 | 0.81 | CHRNA7 (0.47) | ALDH1A1SMN1; SMN2CHRNA7KDM4EGAA | |
| SCHEMBL8243898 | 0.79 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL14590618 | 0.79 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL22320273 | 0.78 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPT | |
| Iodomethane SCHEMBL11745036 | 0.77 | CHRNA7 (0.44) | ALDH1A1SMN1; SMN2CHRNA7KDM4EGAA | |
| SCHEMBL11747608 | 0.74 | CHRNA7 (0.41) | ALDH1A1SMN1; SMN2KMT2ACHRNA7KDM4E | |
| SCHEMBL11747776 | 0.73 | DRD2 (0.46) | ALDH1A1SMN1; SMN2CHRNA7KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354746-A | Prostaglandin inhibitor, analgesics | G. D. SEARLE & CO. (US) | 1994-10-11 | — | — | US | disclosed |