Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | HNF4A | P41235 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | USP7 | Q93009 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10770174 | 0.86 | GABRA1 (0.50) | HDAC4HDAC2HDAC8HDAC6GABRA1 | |
| SCHEMBL22319170 | 0.85 | ELANE (0.44) | HDAC4HDAC2HDAC8HDAC6HNF4A | |
| SCHEMBL29287974 | 0.84 | DHFR (0.41) | HDAC4HDAC2HDAC8HDAC6USP7 | |
| SCHEMBL19567446 | 0.83 | PDCD1 (0.46) | HDAC4HDAC2HDAC8HDAC6GABRA1 | |
| SCHEMBL19566867 | 0.81 | HDAC4 (0.44) | HDAC4HDAC2HDAC8HDAC6GABRA1 | |
| SCHEMBL27759679 | 0.81 | MAPT (0.48) | GABRA1GABRB2KDM4ERCE1ESR2 | |
| SCHEMBL5988340 | 0.80 | ELANE (0.49) | KDM4E | |
| SCHEMBL10905320 | 0.79 | ELANE (0.53) | HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL10911038 | 0.78 | GABRA1 (0.61) | HDAC4HDAC2HDAC8HDAC6GABRA1 | |
| SCHEMBL28945564 | 0.78 | DHFR (0.37) | HDAC4HDAC2HDAC8HDAC6USP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312461-A | Dihydrocarbyl substituted phenylenediamine-derived phenolic products as antioxidants | MOBIL OIL CORPORATION (US) | 1994-05-17 | — | — | US | claimed |
| US-5207939-A | Lubricants with oxidation resistance | MOBIL OIL CORPORATION (US) | 1993-05-04 | — | — | US | claimed |
| US-5312461-A | Dihydrocarbyl substituted phenylenediamine-derived phenolic products as antioxidants | MOBIL OIL CORPORATION (US) | 1994-05-17 | — | — | US | disclosed |
| US-5207939-A | Lubricants with oxidation resistance | MOBIL OIL CORPORATION (US) | 1993-05-04 | — | — | US | disclosed |