Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150813 | 0.85 | CYP3A4 (0.56) | CYP3A4ALDH1A1TSHRKMT2ACYP1A2 | |
| SCHEMBL30927087 | 0.80 | CYP3A4 (0.73) | CYP3A4ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL128215 | 0.80 | CYP3A4 (0.73) | CYP3A4ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL1276647 | 0.78 | INSR (0.46) | CYP3A4ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL9678088 | 0.77 | CYP3A4 (0.56) | CYP3A4ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL12682436 | 0.77 | CYP3A4 (0.69) | CYP3A4ALDH1A1TSHRMEN1KMT2A | |
| Piperonyl Butoxide SCHEMBL8603873 | 0.76 | CYP3A4 (0.85) | CYP3A4ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL1395801 | 0.76 | ALDH1A1 (0.51) | CYP3A4ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL9148810 | 0.76 | MEN1 (0.48) | CYP3A4ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL1520419 | 0.76 | MEN1 (0.48) | CYP3A4ALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5315018-A | Process for the functionalization of organic molecules | ROUSSEL-UCLAF (FR) | 1994-05-24 | — | — | US | disclosed |