⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9490957 | 0.85 | — | — | |
| SCHEMBL9424195 | 0.78 | — | — | |
| SCHEMBL7052812 | 0.77 | — | — | |
| SCHEMBL7052807 | 0.77 | — | — | |
| SCHEMBL9511004 | 0.77 | AGTR1 (0.63) | — | |
| SCHEMBL9490011 | 0.76 | — | — | |
| SCHEMBL7277636 | 0.73 | — | — | |
| SCHEMBL9207265 | 0.73 | — | — | |
| SCHEMBL8536231 | 0.72 | — | — | |
| SCHEMBL8954217 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312828-A | Substituted imidazoles having angiotensin II receptor blocking activity | SMITHKLINE BEECHAM CORPORATION A CORP. OF PENNSYLVANIA | 1994-05-17 | — | — | US | disclosed |