Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | AR | P10275 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | HTR6 | P50406 | 1/20 | 0.58 |
| ▸ | ESRRG | P62508 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 7/20 | 0.54 |
| ▸ | CNR2 | P34972 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187252 | 0.86 | ESR1 (0.56) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| SCHEMBL13589368 | 0.85 | ESR1 (0.59) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| SCHEMBL7082572 | 0.80 | ESR2 (0.53) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| SCHEMBL10923475 | 0.80 | LMNA (0.58) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| SCHEMBL11603039 | 0.79 | ESR1 (0.57) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| SCHEMBL5075019 | 0.79 | ESR1 (0.70) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| SCHEMBL30549330 | 0.79 | ESR1 (0.70) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| SCHEMBL28325930 | 0.79 | KLF10 (0.49) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| Bisphenol A SCHEMBL5141906 | 0.78 | ESR1 (0.84) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| SCHEMBL3149692 | 0.78 | ESR1 (0.84) | ESR1ESR2CYP3A4HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623050-A1 | META, PARA-BISPHENOL BASED POLYMER GAS SEPARATION MEMBRANES | THE DOW CHEMICAL COMPANY (US) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993012869-A1 | META, PARA-BISPHENOL BASED POLYMER GAS SEPARATION MEMBRANES | THE DOW CHEMICAL COMPANY (US) | 1993-07-08 | — | — | WO | disclosed |
| US-5152811-A | Composite membrane | THE DOW CHEMICAL COMPANY (US) | 1992-10-06 | — | — | US | disclosed |