SCHEMBL94247

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL94749	1.00	PGR (0.79)	PGRHDAC1NR1H4KCNQ3KCNQ2
	SCHEMBL22192258	0.92	PGR (0.93)	PGRHDAC1NR1H4KCNQ3KCNQ2
	SCHEMBL5694520	0.89	PGR (1.00)	PGRHDAC1NR1H4KCNQ3KCNQ2
	SCHEMBL19619022	0.89	PGR (0.86)	PGRHDAC1NR1H4KCNQ3KCNQ2
	SCHEMBL8361085	0.87	PGR (0.96)	PGRHDAC1NR1H4RAB9ANPC1
	SCHEMBL95395	0.87	NR1H4 (0.68)	PGRNR1H4RAB9ANPC1TP53
	SCHEMBL94989	0.87	PGR (0.68)	PGRNR1H4RAB9ANPC1CASP3
	SCHEMBL7259582	0.86	PGR (0.81)	PGRHDAC1NR1H4KCNQ3KCNQ2
	SCHEMBL19501833	0.86	PGR (0.81)	PGRHDAC1NR1H4KCNQ3KCNQ2
	SCHEMBL94763	0.85	PTPN1 (0.71)	HDAC1RAB9ANPC1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.