Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9425250 | 0.77 | LMNA (0.36) | GLAGAALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9424861 | 0.76 | LMNA (0.42) | GLAGAALMNARXFP1SMN1; SMN2 | |
| SCHEMBL3900538 | 0.76 | MAPT (0.45) | GLAGAASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL9425135 | 0.74 | HDAC3 (0.47) | LMNARXFP1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL9424969 | 0.72 | CDK2 (0.35) | GAALMNAALDH1A1CDK2RAB9A | |
| SCHEMBL7590081 | 0.66 | PDE10A (0.58) | LMNAALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL3909189 | 0.65 | MAPT (0.44) | GLAGAARXFP1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9842693 | 0.65 | PDE10A (0.57) | LMNAALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL9330916 | 0.64 | ALDH1A1 (0.52) | GLAGAASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL9424812 | 0.63 | PARP1 (0.46) | LMNAL3MBTL1KMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5290936-A | Indicators or labels for antibodies or medical diagnosis | LONDON DIAGNOSTICS, INC. (US) | 1994-03-01 | — | — | US | disclosed |
| US-5284951-A | Aryl ester, thioester or amide of carboxylic acid substituted heterocyclic ring; quaternary compounds | LONDON DIAGNOSTICS, INC. (US) | 1994-02-08 | — | — | US | disclosed |
| US-5283334-A | Side-chain functional chemiluminescent labels and their conjugates, and assays therefrom | LONDON DIAGNOSTICS, INC. (US) | 1994-02-01 | — | — | US | disclosed |