Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516168 | 0.85 | ALDH1A1 (0.32) | TSHRALDH1A1L3MBTL1TGFBR1 | |
| SCHEMBL729016 | 0.81 | MAPT (0.50) | TSHRMAPTCACNA1BAPBA1KMT2A | |
| SCHEMBL357937 | 0.78 | ALDH1A1 (0.49) | TSHRKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL1172960 | 0.76 | MAPT (0.45) | TSHRMAPTCACNA1BAPBA1ALDH1A1 | |
| SCHEMBL6993745 | 0.76 | MAPT (0.43) | TSHRMAPTCACNA1BAPBA1KMT2A | |
| SCHEMBL2930578 | 0.76 | ALDH1A1 (0.34) | TSHRALDH1A1GAAL3MBTL1TGFBR1 | |
| SCHEMBL1076421 | 0.75 | MAPT (0.46) | TSHRMAPTCACNA1BAPBA1KMT2A | |
| SCHEMBL1023939 | 0.75 | MAPT (0.60) | TSHRMAPTCACNA1BAPBA1KMT2A | |
| SCHEMBL2930085 | 0.74 | TSHR (0.40) | TSHRALDH1A1KDM4EMAPK1L3MBTL1 | |
| SCHEMBL9425493 | 0.74 | MAPT (0.48) | TSHRMAPTCACNA1BAPBA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354495-A | Homo- or copolymerizable through ethylenic unsaturation | NIPPON PAINT CO., LTD. (JP) | 1994-10-11 | — | — | US | disclosed |
| EP-0177122-B1 | ACRYLAMIDE DERIVATIVES | Nippon Paint Co., Ltd. (JP) | 1992-04-01 | — | — | EP | disclosed |
| US-4935413-A | ELASTICITY, ADHESION AND DISPERSIBILITY | NIPPON PAINT CO., LTD. (JP) | 1990-06-19 | — | — | US | disclosed |
| EP-0177122-A2 | Acrylamide derivatives | Nippon Paint Co., Ltd. (JP) | 1986-04-09 | — | — | EP | disclosed |