Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | BAD | Q92934 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716210 | 0.87 | PTGS2 (0.41) | L3MBTL1PTGS2ALDH1A1 | |
| SCHEMBL8305012 | 0.81 | L3MBTL1 (0.45) | L3MBTL1PTGS2TSHRALDH1A1BCL2L1 | |
| SCHEMBL4418630 | 0.79 | PTGS2 (0.44) | L3MBTL1PTGS2ALDH1A1MEN1KMT2A | |
| SCHEMBL8470197 | 0.75 | L3MBTL1 (0.41) | ACHEL3MBTL1PTGS2ALDH1A1MEN1 | |
| SCHEMBL1795678 | 0.72 | TNKS2 (0.37) | ACHEPTGS2TSHRALDH1A1MEN1 | |
| SCHEMBL10300262 | 0.68 | BCL2L1 (0.55) | ACHEBCL2L1BADLPLLIPG | |
| SCHEMBL10337645 | 0.68 | BCL2L1 (0.55) | ACHEBCL2L1BADLPLLIPG | |
| SCHEMBL12562793 | 0.68 | BCL2L1 (0.55) | ACHEBCL2L1BADLPLLIPG | |
| SCHEMBL197346 | 0.68 | BCL2L1 (0.55) | ACHEBCL2L1BADLPLLIPG | |
| SCHEMBL539461 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5334600-A | Lipoxygenase inhibitors | CIBA-GEIGY CORPORATION (US) | 1994-08-02 | — | — | US | disclosed |