Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 2/20 | 0.76 |
| ▸ | PTGS2 | P35354 | 14/20 | 0.64 |
| ▸ | CLCN2 | P51788 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
| ▸ | TTR | P02766 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | FABP2 | P12104 | 1/20 | 0.57 |
| ▸ | RXRA | P19793 | 1/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.57 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | PDE4A | P27815 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terofenamate SCHEMBL4742611 | 0.96 | METTL3 (0.79) | METTL3PTGS2CLCN2MEN1MAPK1 | |
| Terofenamate SCHEMBL7705424 | 0.95 | METTL3 (0.78) | METTL3PTGS2CLCN2MEN1MAPK1 | |
| Terofenamate SCHEMBL5089764 | 0.95 | METTL3 (0.81) | METTL3PTGS2CLCN2MEN1MAPK1 | |
| Terofenamate SCHEMBL26088 | 0.95 | METTL3 (0.84) | METTL3PTGS2CLCN2MEN1MAPK1 | |
| Terofenamate SCHEMBL29483481 | 0.95 | METTL3 (0.84) | METTL3PTGS2CLCN2MEN1MAPK1 | |
| Terofenamate SCHEMBL9659644 | 0.94 | METTL3 (0.76) | METTL3PTGS2CLCN2MEN1MAPK1 | |
| Terofenamate SCHEMBL3805644 | 0.94 | METTL3 (0.79) | METTL3PTGS2CLCN2MEN1MAPK1 | |
| Terofenamate SCHEMBL8814628 | 0.94 | METTL3 (0.83) | METTL3PTGS2CLCN2MEN1MAPK1 | |
| Terofenamate SCHEMBL15537603 | 0.94 | METTL3 (0.83) | METTL3PTGS2CLCN2MEN1MAPK1 | |
| Terofenamate SCHEMBL1206761 | 0.94 | METTL3 (0.83) | METTL3PTGS2CLCN2MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276149-A | Antibiotics | MERCK & CO., INC. (US) | 1994-01-04 | — | — | US | disclosed |
| EP-0538017-A1 | 2-(N-Imidazoliumphenyl)-carbapenems | MERCK & CO. INC. (US) | 1993-04-21 | — | — | EP | disclosed |