Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4351535 | 0.83 | KDM4E (0.65) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL9428963 | 0.81 | KDM4E (0.58) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL27476489 | 0.78 | PARP1 (0.54) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL7826233 | 0.77 | KDM4E (0.59) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL30130273 | 0.77 | KDM4E (0.59) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL5749326 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL5188827 | 0.77 | KDM4E (0.67) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL4383121 | 0.73 | TDP1 (0.58) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL997090 | 0.73 | AKR1B1 (0.56) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL5748553 | 0.72 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5348890-A | In an aqueous solvent | NOF CORPORATION (JP) | 1994-09-20 | — | — | US | disclosed |
| EP-0545367-A1 | Trioxane derivatives, process for the preparation thereof, and method for the chemiluminescence | NOF CORPORATION (JP) | 1993-06-09 | — | — | EP | disclosed |