SCHEMBL4351535

SCHEMBL4351535

O=C(O)Cc1c2ccccc2cc2ccccc12

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.65
ALDH1A1 P00352 3/20 0.65
GLA P06280 3/20 0.65
HPGD P15428 2/20 0.65
HSD17B10 Q99714 2/20 0.65
GAA P10253 2/20 0.65
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
CYP1A2 P05177 1/20 0.55
CYP2C19 P33261 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
AKR1B1 P15121 4/20 0.53
HTR2A P28223 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
GPR35 Q9HC97 2/20 0.51
POLB P06746 1/20 0.51
MAPT P10636 1/20 0.47
CASP1 P29466 1/20 0.47
CASP7 P55210 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9428963 0.86 KDM4E (0.58) KDM4EALDH1A1GLAHPGDHSD17B10
SCHEMBL4383121 0.85 TDP1 (0.58) KDM4EALDH1A1GLAHPGDHSD17B10
SCHEMBL30130273 0.84 KDM4E (0.59) KDM4EALDH1A1GLAHPGDHSD17B10
SCHEMBL7826233 0.84 KDM4E (0.59) KDM4EALDH1A1GLAHPGDHSD17B10
SCHEMBL9425440 0.83 ALDH1A1 (0.51) KDM4EALDH1A1GLAHPGDHSD17B10
SCHEMBL29261872 0.82 KDM4E (0.54) KDM4EALDH1A1GLAHPGDHSD17B10
SCHEMBL10404287 0.82 L3MBTL1 (0.55) KDM4EALDH1A1GLAHPGDHSD17B10
SCHEMBL28195038 0.82 HTR2A (0.50) KDM4EALDH1A1GLAHPGDHSD17B10
SCHEMBL1497455 0.81 KDM4E (0.48) KDM4EALDH1A1GLAHPGDHSD17B10
SCHEMBL1882693 0.80 MEN1 (0.53) KDM4EALDH1A1GLAHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111718395-A Prodrug activating compound, prodrug system, preparation method and application thereof 国家纳米科学中心 2020-09-29 CN claimed
CN-111718395-B Prodrug activating compound, prodrug system, preparation method and application thereof 国家纳米科学中心 2022-03-18 CN disclosed
CN-113292711-A Method for synthesizing fluorescent functional polyester-based amphiphilic polymer 安阳工学院 2021-08-24 CN disclosed
CN-111718395-A Prodrug activating compound, prodrug system, preparation method and application thereof 国家纳米科学中心 2020-09-29 CN disclosed
CN-110330420-B Process for preparing acids with different substituents 湖南大学 2020-07-10 CN disclosed
CN-111378155-A Energy absorption method based on dynamic polymer 翁秋梅 2020-07-07 CN disclosed
CN-106125509-B LED-curable liquid resin composition for additive fabrication 帝斯曼知识产权资产管理有限公司 2019-12-17 CN disclosed
US-20090275694-A1 Spin-on-Glass Anti-Reflective Coatings for Photolithography HONEYWELL INTERNATIONAL INC. (US) 2009-11-05 US disclosed
EP-1478681-A4 SPIN-ON-GLASS ANTI-REFLECTIVE COATINGS FOR PHOTOLITHOGRAPHY HONEYWELL INT INC (US) 2006-10-11 EP disclosed
EP-1478681-A1 SPIN-ON-GLASS ANTI-REFLECTIVE COATINGS FOR PHOTOLITHOGRAPHY Honeywell International, Inc. (US) 2004-11-24 EP disclosed
WO-2003044077-A1 SPIN-ON-GLASS ANTI-REFLECTIVE COATINGS FOR PHOTOLITHOGRAPHY HONEYWELL INTERNATIONAL INC. (US) 2003-05-30 WO disclosed