Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 4/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.49 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
| ▸ | CASP2 | P42575 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | GLP1R | P43220 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920199 | 0.91 | DGKA (0.67) | DGKAL3MBTL1FAAHDNM1LPAR1 | |
| SCHEMBL20856388 | 0.91 | DGKA (0.67) | DGKAL3MBTL1FAAHDNM1LPAR1 | |
| SCHEMBL8921681 | 0.91 | DGKA (0.67) | DGKAL3MBTL1FAAHDNM1LPAR1 | |
| SCHEMBL8921826 | 0.91 | DGKA (0.67) | DGKAL3MBTL1FAAHDNM1LPAR1 | |
| SCHEMBL8920345 | 0.91 | DGKA (0.67) | DGKAL3MBTL1FAAHDNM1LPAR1 | |
| SCHEMBL8922042 | 0.91 | DGKA (0.67) | DGKAL3MBTL1FAAHDNM1LPAR1 | |
| SCHEMBL303966 | 0.91 | DGKA (0.67) | DGKAL3MBTL1FAAHDNM1LPAR1 | |
| SCHEMBL7650140 | 0.91 | FAAH (0.62) | EPHX2FAAHDNM1LPAR1LPAR2 | |
| SCHEMBL7647954 | 0.91 | FAAH (0.62) | EPHX2FAAHDNM1LPAR1LPAR2 | |
| SCHEMBL13811075 | 0.91 | FAAH (0.62) | EPHX2FAAHDNM1LPAR1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358946-A | Heterocycle-substituted amides, carbamates and ureas as agents for the treatment of atherosclerosis | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-10-25 | — | — | US | disclosed |