Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | BCR | P11274 | 2/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 16/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9425969 | 0.80 | BRAF (0.36) | KCNJ11MEN1LMNAPOLBKMT2A | |
| SCHEMBL9425967 | 0.80 | BRAF (0.36) | KCNJ11MEN1LMNAPOLBKMT2A | |
| SCHEMBL7361551 | 0.79 | TACR3 (0.40) | SMN1; SMN2 | |
| SCHEMBL7361549 | 0.79 | TACR3 (0.40) | SMN1; SMN2 | |
| SCHEMBL9425856 | 0.79 | KCNJ11 (0.57) | KCNJ11LMNA | |
| Sulfuric Acid SCHEMBL10447918 | 0.76 | ABCC9 (0.47) | KCNJ11MEN1LMNAKMT2A | |
| SCHEMBL10446808 | 0.75 | KCNJ11 (0.41) | KCNJ11MEN1LMNAPOLBKMT2A | |
| SCHEMBL9456838 | 0.74 | ABCC9 (0.51) | KCNJ11MEN1LMNAKMT2A | |
| Naminidil SCHEMBL7639234 | 0.73 | ABCC9 (0.56) | KCNJ11MEN1LMNAPOLBKMT2A | |
| Pinacidil Anhydrous SCHEMBL2131822 | 0.73 | ABCC9 (0.56) | KCNJ11MEN1LMNAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371086-A | Circulatory disorders side effect reduction | THE GREEN CROSS CORPORATION (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5262415-A | FOR TREATING DISEASES OF THE CIRCULATORY SYSTEM | THE GREEN CROSS CORPORATION (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0503627-A1 | Aminopyridine compounds | THE GREEN CROSS CORPORATION (JP) | 1992-09-16 | — | — | EP | disclosed |