Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9425905 | 1.00 | GAA (0.31) | GAAKDM4EALDH1A1GLAHDAC1 | |
| SCHEMBL22147348 | 0.77 | CYP3A4 (0.41) | GAAKDM4EALDH1A1GLA | |
| SCHEMBL161843 | 0.77 | CYP3A4 (0.41) | GAAKDM4EALDH1A1GLA | |
| SCHEMBL161844 | 0.77 | CYP3A4 (0.41) | GAAKDM4EALDH1A1GLA | |
| SCHEMBL162151 | 0.74 | LMNA (0.52) | GAAKDM4EALDH1A1 | |
| SCHEMBL162150 | 0.74 | LMNA (0.52) | GAAKDM4EALDH1A1 | |
| SCHEMBL13106903 | 0.69 | RAF1 (0.42) | GAAKDM4EALDH1A1 | |
| SCHEMBL9425909 | 0.69 | SMN1; SMN2 (0.44) | GAAKDM4EALDH1A1GLA | |
| SCHEMBL9426597 | 0.69 | GAA (0.42) | GAAKDM4EALDH1A1HDAC1HDAC2 | |
| SCHEMBL9426603 | 0.69 | GAA (0.42) | GAAKDM4EALDH1A1HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371086-A | Circulatory disorders side effect reduction | THE GREEN CROSS CORPORATION (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5262415-A | FOR TREATING DISEASES OF THE CIRCULATORY SYSTEM | THE GREEN CROSS CORPORATION (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0503627-A1 | Aminopyridine compounds | THE GREEN CROSS CORPORATION (JP) | 1992-09-16 | — | — | EP | disclosed |