Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1309528 | 0.76 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1CYP3A4HSD17B10GLA | |
| SCHEMBL7978023 | 0.76 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1CYP3A4HSD17B10GLA | |
| SCHEMBL11168013 | 0.74 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1CYP3A4CYP1A2ABCC9 | |
| SCHEMBL9425907 | 0.69 | GAA (0.31) | ALDH1A1GLAGAAKDM4E | |
| SCHEMBL9425905 | 0.69 | GAA (0.31) | ALDH1A1GLAGAAKDM4E | |
| SCHEMBL9426610 | 0.69 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1MAPTGAA | |
| SCHEMBL7979663 | 0.67 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7979665 | 0.67 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3287569 | 0.66 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3287572 | 0.66 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371086-A | Circulatory disorders side effect reduction | THE GREEN CROSS CORPORATION (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5262415-A | FOR TREATING DISEASES OF THE CIRCULATORY SYSTEM | THE GREEN CROSS CORPORATION (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0503627-A1 | Aminopyridine compounds | THE GREEN CROSS CORPORATION (JP) | 1992-09-16 | — | — | EP | disclosed |