Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 13/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9425346 | 0.87 | LMNA (0.47) | LMNAMAPK1HTTSMN1; SMN2GRM2 | |
| SCHEMBL9815504 | 0.83 | GRM2 (0.50) | GRM2 | |
| SCHEMBL10879568 | 0.82 | GRM2 (0.43) | GRM2F10 | |
| SCHEMBL9425768 | 0.78 | GRM2 (0.44) | GRM2F10 | |
| SCHEMBL8120057 | 0.78 | GRM2 (0.64) | GRM2F10 | |
| SCHEMBL7298956 | 0.76 | GRM2 (0.69) | GRM2F10 | |
| SCHEMBL6861651 | 0.73 | GRM2 (0.67) | GRM2 | |
| SCHEMBL11246864 | 0.73 | GRM2 (0.49) | GRM2F10 | |
| SCHEMBL11592601 | 0.73 | GRM2 (0.60) | GRM2 | |
| SCHEMBL10879427 | 0.73 | GRM2 (0.44) | GRM2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5278179-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-01-11 | — | — | US | claimed |
| EP-0518153-A1 | Substituted oxazolidinones as pesticidal agents, new substituted oxazolidinones, their preparation and utilization | BAYER AG (DE) | 1992-12-16 | — | — | EP | claimed |
| US-5278179-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-01-11 | — | — | US | disclosed |
| EP-0518153-A1 | Substituted oxazolidinones as pesticidal agents, new substituted oxazolidinones, their preparation and utilization | BAYER AG (DE) | 1992-12-16 | — | — | EP | disclosed |