SCHEMBL9815504

SCHEMBL9815504

CS(=O)(=O)c1ccc(N2CC(CCl)OC2=O)cc1

nearest known ligand 0.50

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 15/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9815526 0.86 MAOA (0.56) GRM2
SCHEMBL11594531 0.86 GRM2 (0.50) GRM2
SCHEMBL9815590 0.86 F10 (0.57) GRM2
SCHEMBL10878982 0.86 MAOA (0.56) GRM2
SCHEMBL9815487 0.86 GRM2 (0.50) GRM2
SCHEMBL9815496 0.86 GRM2 (0.50) GRM2
SCHEMBL11063235 0.84 GRM2 (0.51) GRM2
SCHEMBL10879568 0.83 GRM2 (0.43) GRM2
SCHEMBL22245004 0.83 CALML3 (0.55) GRM2
SCHEMBL9425940 0.83 LMNA (0.47) GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4128654-A BACTERICIDE, FUNGICIDE, PLANT DISEASES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-12-05 US claimed
EP-0127902-B1 AMINOMETHYL OXOOXAZOLIDINYL BENZENE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-10-16 EP disclosed
US-4705799-A Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-11-10 US disclosed
EP-0050827-B1 3-(P-ALKYLSULFONYLPHENYL)-AND 3-(P-ALKYLSULFINYLPHENYL)OXAZOLIDINONE DERIVATIVES AS ANTI-BACTERIAL AGENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-04-30 EP disclosed
EP-0127902-A2 Aminomethyl oxooxazolidinyl benzene derivatives useful as antibacterial agents E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-12-12 EP disclosed
US-4340606-A 3-(p-Alkylsulfonylphenyl)oxazolidinone derivatives as antibacterial agents E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-07-20 US disclosed
EP-0050827-A1 3-(p-Alkylsulfonylphenyl)-and 3-(p-alkylsulfinylphenyl)oxazolidinone derivatives as anti-bacterial agents E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-05-05 EP disclosed
US-4128654-A BACTERICIDE, FUNGICIDE, PLANT DISEASES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-12-05 US disclosed