Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RHOA | P61586 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1024005 | 0.81 | TSHR (0.40) | MAPTCACNA1BAPBA1TSHRCYP3A4 | |
| SCHEMBL465993 | 0.81 | TSHR (0.40) | MAPTCACNA1BAPBA1TSHRCYP3A4 | |
| SCHEMBL15641518 | 0.75 | MAPT (0.43) | MAPTCACNA1BAPBA1TSHRCYP3A4 | |
| SCHEMBL875124 | 0.75 | TDP1 (0.50) | MAPTCACNA1BAPBA1TSHRCYP3A4 | |
| SCHEMBL28214328 | 0.73 | ALOX15 (0.35) | ALDH1A1TDP1HSD17B10ALOX15 | |
| SCHEMBL29220303 | 0.73 | TSHR (0.44) | MAPTCACNA1BAPBA1TSHRCYP3A4 | |
| SCHEMBL28541016 | 0.73 | ALOX15 (0.52) | MAPTTSHRCYP3A4ALDH1A1TDP1 | |
| Methylamine SCHEMBL5316668 | 0.73 | — | — | |
| SCHEMBL2829656 | 0.73 | ALOX15 (0.52) | MAPTTSHRCYP3A4ALDH1A1TDP1 | |
| SCHEMBL5716647 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0580765-A1 | METAL TREATMENT | HENKEL CORPORATION (US) | 1994-02-02 | — | — | EP | disclosed |
| WO-1992018661-A1 | METAL TREATMENT | HENKEL CORPORATION (US) | 1992-10-29 | — | — | WO | disclosed |