Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23009384 | 0.81 | KMT2A (0.51) | GPBAR1KMT2APOLBKDM4ESRC | |
| SCHEMBL482526 | 0.73 | KMT2A (0.59) | KMT2APOLBKDM4EPKMPGR | |
| SCHEMBL486173 | 0.72 | SMN1; SMN2 (0.47) | KMT2APOLBMAPTPGRHTT | |
| SCHEMBL6861323 | 0.72 | KMT2A (0.36) | KMT2APOLBKDM4EMAPTPKM | |
| SCHEMBL12173033 | 0.71 | MEN1 (0.49) | GPBAR1KMT2AMEN1PGRNR1H3 | |
| SCHEMBL2483553 | 0.71 | POLB (0.32) | KMT2APOLBKDM4EMAPT | |
| SCHEMBL5404611 | 0.71 | PLAU (0.33) | KMT2APOLBKDM4EMAPT | |
| SCHEMBL2038462 | 0.70 | MAPT (0.40) | KMT2AKDM4EGAAMAPTMEN1 | |
| SCHEMBL11770408 | 0.69 | KMT2A (0.64) | HDAC6KMT2APOLBKDM4EPKM | |
| SCHEMBL2535672 | 0.68 | PGR (0.41) | KMT2AMEN1PGRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360819-A | Nonradioactive labels which provide a ketone signal, vapor phase analysis | NORTHEASTERN UNIVERSITY (US) | 1994-11-01 | — | — | US | disclosed |