Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 10/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | EBP | Q15125 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9426585 | 0.89 | SIGMAR1 (0.52) | KCNH2EBPSIGMAR1 | |
| SCHEMBL9426658 | 0.87 | SIGMAR1 (0.46) | KCNH2EBPSIGMAR1 | |
| SCHEMBL9426759 | 0.87 | SIGMAR1 (0.46) | KCNH2EBPSIGMAR1 | |
| SCHEMBL9426893 | 0.87 | SIGMAR1 (0.46) | KCNH2EBPSIGMAR1 | |
| SCHEMBL9426230 | 0.87 | SIGMAR1 (0.46) | KCNH2EBPSIGMAR1 | |
| SCHEMBL9426668 | 0.87 | CYP4F2 (0.42) | KCNH2SMPD1EBPSIGMAR1LTA4H | |
| SCHEMBL9426319 | 0.86 | SIGMAR1 (0.52) | KCNH2AOC3EBPSIGMAR1 | |
| SCHEMBL9426455 | 0.86 | SIGMAR1 (0.45) | KCNH2AOC3EBPSIGMAR1 | |
| SCHEMBL9426200 | 0.83 | SIGMAR1 (0.50) | KCNH2EBPSIGMAR1LTA4H | |
| SCHEMBL9426919 | 0.81 | KCNH2 (0.49) | KCNH2EBPSIGMAR1LTA4HACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5302595-A | Muscarinic receptor antagonists | PFIZER INC. (US) | 1994-04-12 | — | — | US | disclosed |
| US-5219871-A | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1993-06-15 | — | — | US | disclosed |
| EP-0364123-B1 | MUSCARINIC RECEPTOR ANTAGONISTS | Pfizer Limited (GB) | 1991-06-12 | — | — | EP | disclosed |
| EP-0364123-A1 | Muscarinic receptor antagonists | Pfizer Limited (GB) | 1990-04-18 | — | — | EP | disclosed |