Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.46 |
| ▸ | EBP | Q15125 | 3/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | FDPS | P14324 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9426585 | 0.92 | SIGMAR1 (0.52) | SIGMAR1EBPCHRM2CHRM1CHRM3 | |
| SCHEMBL9426893 | 0.90 | SIGMAR1 (0.46) | SIGMAR1EBPCHRM2CHRM1CHRM3 | |
| SCHEMBL9426759 | 0.90 | SIGMAR1 (0.46) | SIGMAR1EBPCHRM2CHRM1CHRM3 | |
| SCHEMBL9426230 | 0.90 | SIGMAR1 (0.46) | SIGMAR1EBPCHRM2CHRM1CHRM3 | |
| SCHEMBL9426319 | 0.89 | SIGMAR1 (0.52) | SIGMAR1EBPCHRM2CHRM1CHRM3 | |
| SCHEMBL9426455 | 0.89 | SIGMAR1 (0.45) | SIGMAR1EBPCHRM2CHRM1CHRM3 | |
| SCHEMBL9426928 | 0.87 | FDPS (0.50) | SIGMAR1EBPCHRM2CHRM1CHRM3 | |
| SCHEMBL9426288 | 0.87 | KCNH2 (0.51) | SIGMAR1EBPKCNH2 | |
| SCHEMBL9426200 | 0.86 | SIGMAR1 (0.50) | SIGMAR1EBPCHRM2CHRM1CHRM3 | |
| SCHEMBL9426668 | 0.85 | CYP4F2 (0.42) | SIGMAR1EBPCHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5302595-A | Muscarinic receptor antagonists | PFIZER INC. (US) | 1994-04-12 | — | — | US | disclosed |
| US-5219871-A | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1993-06-15 | — | — | US | disclosed |
| EP-0364123-B1 | MUSCARINIC RECEPTOR ANTAGONISTS | Pfizer Limited (GB) | 1991-06-12 | — | — | EP | disclosed |
| EP-0364123-A1 | Muscarinic receptor antagonists | Pfizer Limited (GB) | 1990-04-18 | — | — | EP | disclosed |