Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B3 | Q9NPD5 | 4/20 | 0.82 |
| ▸ | SLCO1B1 | Q9Y6L6 | 4/20 | 0.82 |
| ▸ | SLCO2B1 | O94956 | 3/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.71 |
| ▸ | RECQL | P46063 | 2/20 | 0.71 |
| ▸ | SOST | Q9BQB4 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.71 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | SYNJ2 | O15056 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Silicristin A SCHEMBL971442 | 0.90 | SLCO1B3 (1.00) | SLCO1B3SLCO1B1SLCO2B1CYP3A4ALOX15 | |
| Silicristin A SCHEMBL10049339 | 0.90 | SLCO1B3 (1.00) | SLCO1B3SLCO1B1SLCO2B1CYP3A4ALOX15 | |
| Silicristin SCHEMBL29388135 | 0.90 | SLCO1B3 (1.00) | SLCO1B3SLCO1B1SLCO2B1CYP3A4ALOX15 | |
| Silicristin A SCHEMBL29977624 | 0.90 | SLCO1B3 (1.00) | SLCO1B3SLCO1B1SLCO2B1CYP3A4ALOX15 | |
| Silicristin A SCHEMBL12871270 | 0.90 | SLCO1B3 (1.00) | SLCO1B3SLCO1B1SLCO2B1CYP3A4ALOX15 | |
| Silicristin A SCHEMBL4654076 | 0.90 | SLCO1B3 (1.00) | SLCO1B3SLCO1B1SLCO2B1CYP3A4ALOX15 | |
| Silicristin B SCHEMBL20152103 | 0.90 | SLCO1B3 (1.00) | SLCO1B3SLCO1B1SLCO2B1CYP3A4ALOX15 | |
| Silicristin B SCHEMBL29420864 | 0.90 | SLCO1B3 (1.00) | SLCO1B3SLCO1B1SLCO2B1CYP3A4ALOX15 | |
| Silicristin A SCHEMBL22571311 | 0.90 | SLCO1B3 (1.00) | SLCO1B3SLCO1B1SLCO2B1CYP3A4ALOX15 | |
| SCHEMBL17663665 | 0.88 | SLCO1B3 (0.90) | SLCO1B3SLCO1B1SLCO2B1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2141 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122031742-A | Starch film slow-release patch for promoting wound healing and preparation method thereof | 咸阳职业技术学院 | 2026-05-15 | — | — | CN | claimed |
| EP-4734943-A1 | PERSONAL CARE COMPOSITION COMPRISING A CARBOXYMETHYL CYSTEINE COMPOUND AND A SILYMARIN COMPOUND | Unilever IP Holdings B.V. (NL) | 2026-05-06 | — | — | EP | claimed |
| US-20260091073-A1 | COMPOSITIONS CONTAINING SILYMARIN AND SULFOALKYL ETHER CYCLODEXTRIN AND METHODS OF USING THE SAME | CYDEX PHARMACEUTICALS INC (US) | 2026-04-02 | — | — | US | claimed |
| EP-4663188-A1 | USE OF SILYBUM MARIANUM PHARMACEUTICAL COMPOSITION IN PREPARATION OF DRUGS FOR TREATING FATTY LIVER DISEASES | Health and Happiness (H&H) Hong Kong Limited (HK) | 2025-12-17 | — | — | EP | claimed |
| EP-4620534-A2 | COMPOSITIONS CONTAINING SILYMARIN AND SULFOALKYL ETHER CYCLODEXTRIN AND METHODS OF USING THE SAME | CyDex Pharmaceuticals, Inc. (US) | 2025-09-24 | — | — | EP | claimed |
| US-12390506-B2 | Compositions containing silymarin and sulfoalkyl ether cyclodextrin and methods of using the same | CYDEX PHARMACEUTICALS, INC. (US) | 2025-08-19 | — | — | US | claimed |
| EP-3939582-B1 | COMPOSITIONS CONTAINING SILYMARIN AND SULFOALKYL ETHER CYCLODEXTRIN AND METHODS OF USING THE SAME | CYDEX PHARMACEUTICALS INC (US) | 2025-04-30 | — | — | EP | claimed |
| CN-119770483-A | Application of pharmaceutical composition in preparation of medicine for treating neurodegenerative diseases | 合生元（广州）健康产品有限公司 | 2025-04-08 | — | — | CN | claimed |
| WO-2025024478-A1 | COMPOSITIONS FOR THE MODULATION OF TASTE | IXORA SCIENTIFIC INC. (US) | 2025-01-30 | — | — | WO | claimed |
| WO-2025002724-A1 | PERSONAL CARE COMPOSITION COMPRISING A CARBOXYMETHYL CYSTEINE COMPOUND AND A SILYMARIN COMPOUND | UNILEVER IP HOLDINGS B.V. (NL) | 2025-01-02 | — | — | WO | claimed |
| CN-1111506-A | Formulations containing carotenoids and procarotenoids combined with polyphenols in the prevention of the damages due to an abnormal production of free radicals | INDENA SPA (IT) | 1995-11-15 | — | — | CN | claimed |
| EP-0659402-A2 | Formulations containing carotenoids and procarotenoids combined with polyphenols in the prevention of the damages due to an abnormal production of free radicals | INDENA S.p.A. (IT) | 1995-06-28 | — | — | EP | claimed |
| EP-0300282-B1 | PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING COMPLEXES OF FLAVANOLIGNANS WITH PHOSPHOLIPIDS | INDENA S.p.A. (IT) | 1992-11-11 | — | — | EP | claimed |
| EP-0209037-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING FLAVANOLIGNANES AND PHOSPHOLIPIDS AS ACTIVE PRINCIPLES | I D B HOLDING S.P.A. (IT) | 1990-02-28 | — | — | EP | claimed |
| US-4895839-A | ANTIEDEMIC, SKIN PROTECTION | INDENZA S.p.A. (IT) | 1990-01-23 | — | — | US | claimed |
| EP-0209038-B1 | COMPLEXES OF FLAVANOLIGNANES WITH PHOSPHOLIPIDS, PREPARATION THEREOF AND ASSOCIATED PHARMACEUTICAL COMPOSITIONS | I D B HOLDING S.P.A. (IT) | 1989-09-20 | — | — | EP | claimed |
| EP-0300282-A1 | Pharmaceutical and cosmetic compositions containing complexes of flavanolignans with phospholipids | INDENA S.p.A. (IT) | 1989-01-25 | — | — | EP | claimed |
| US-4764508-A | Complexes of flavanolignans with phospholipids, preparation thereof and associated pharmaceutical compositions | INVERNI DELLA BEFFA S.P.A. (IT) | 1988-08-16 | — | — | US | claimed |
| EP-0209038-A1 | Complexes of flavanolignanes with phospholipids, preparation thereof and associated pharmaceutical compositions | I D B HOLDING S.P.A. (IT) | 1987-01-21 | — | — | EP | claimed |
| EP-0209037-A1 | Pharmaceutical compositions containing flavanolignanes and phospholipids as active principles | I D B HOLDING S.P.A. (IT) | 1987-01-21 | — | — | EP | claimed |