Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 1/20 | 0.68 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.68 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9425845 | 0.90 | CYP3A4 (0.64) | CDK8CLK4LTA4HCYP1A2CYP3A4 | |
| SCHEMBL10877563 | 0.86 | LMNA (0.56) | CDK8CLK4NPC1L3MBTL1CYP1A2 | |
| SCHEMBL9425740 | 0.85 | CDK8 (0.50) | CDK8CLK4APP | |
| SCHEMBL3999705 | 0.83 | CDK8 (0.74) | CDK8CLK4NPC1RAB9AL3MBTL1 | |
| SCHEMBL7273901 | 0.83 | CDK8 (0.63) | CDK8CLK4NPC1RAB9AL3MBTL1 | |
| SCHEMBL8789349 | 0.82 | CDK8 (0.72) | CDK8CLK4NPC1RAB9AL3MBTL1 | |
| SCHEMBL9683503 | 0.81 | APP (0.62) | CDK8CLK4CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9426210 | 0.81 | CDK8 (0.47) | CDK8CLK4LTA4HNPC1RAB9A | |
| SCHEMBL9346628 | 0.80 | IAPP (0.62) | NPC1RAB9ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14815004 | 0.79 | CDK8 (0.61) | CDK8CLK4LTA4HCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338745-A | Alzheimer's disease | MITSUI TOATSU CHEMICALS, INCORPORATION (JP) | 1994-08-16 | — | — | US | disclosed |
| EP-0495998-A1 | DIHYDROCAFFEIC ACID AMIDE DERIVATIVE AND APPLICATION THEREOF AS MEDICINE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-07-29 | — | — | EP | disclosed |