Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | ILK | Q13418 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 3/20 | 0.30 |
| ▸ | RAB9A | P51151 | 3/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3752215 | 0.85 | MAPT (0.33) | MEN1KMT2ATHRBMAPTTP53 | |
| SCHEMBL9368369 | 0.75 | MAPT (0.35) | MEN1KMT2ATHRBMAPTTP53 | |
| SCHEMBL3743974 | 0.75 | PARP1 (0.40) | MEN1KMT2AILKMAPTTP53 | |
| SCHEMBL7059454 | 0.71 | MEN1 (0.38) | MEN1KMT2AILKTHRBMAPT | |
| 1,2,3-Benzothia-Diazole-7-Carboxylic Acid SCHEMBL2455715 | 0.69 | ALDH1A1 (0.44) | MEN1KMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL9363329 | 0.69 | SMN1; SMN2 (0.39) | MEN1KMT2AILKMAPTTP53 | |
| 1,2,3-Benzothia-Diazole-7-Carboxylic Acid SCHEMBL9084433 | 0.68 | ALDH1A1 (0.43) | MEN1KMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL9363650 | 0.68 | ASH1L (0.33) | MAPTTP53SMN1; SMN2 | |
| SCHEMBL8051642 | 0.68 | MAPT (0.45) | MEN1KMT2ATHRBMAPTTP53 | |
| SCHEMBL7555956 | 0.68 | MAPT (0.39) | MEN1KMT2ATHRBMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304652-A | Benzo-1,2,3-thiadiazole derivatives; fungicides | CIBA-GEIGY CORPORATION (US) | 1994-04-19 | — | — | US | disclosed |
| US-5229384-A | Microbiocides | CIBA-GEIGY CORPORATION (US) | 1993-07-20 | — | — | US | disclosed |