Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7461943 | 0.81 | AOC3 (0.43) | KCNA3AOC3LMNAALDH1A1RECQL | |
| SCHEMBL7461946 | 0.81 | AOC3 (0.43) | KCNA3AOC3LMNAALDH1A1RECQL | |
| SCHEMBL1135899 | 0.80 | NDUFS8 (0.49) | KCNA3AOC3LMNAALDH1A1RECQL | |
| SCHEMBL11289126 | 0.79 | LTA4H (0.41) | AOC3LMNAALDH1A1RECQLMTNR1A | |
| SCHEMBL11289133 | 0.79 | LTA4H (0.41) | AOC3LMNAALDH1A1RECQLMTNR1A | |
| SCHEMBL7536951 | 0.77 | TRPV1 (0.56) | ALDH1A1MTNR1AALOX15L3MBTL1 | |
| SCHEMBL11757158 | 0.77 | TRPV1 (0.56) | ALDH1A1MTNR1AALOX15L3MBTL1 | |
| SCHEMBL11639904 | 0.77 | LTA4H (0.55) | AOC3MAOBLTA4H | |
| SCHEMBL11283781 | 0.76 | AOC3 (0.39) | KCNA3AOC3LMNAALDH1A1RECQL | |
| SCHEMBL11289830 | 0.76 | AOC3 (0.39) | AOC3LMNARECQLMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5349105-A | Skin disorder | ALLERGAN, INC. (US) | 1994-09-20 | — | — | US | disclosed |
| US-5202471-A | Skin disorders | ALLERGAN, INC. (US) | 1993-04-13 | — | — | US | disclosed |