Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | DAO | P14920 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | APLNR | P35414 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3030873 | 0.79 | KMT2A (0.54) | ELANEKMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4237894 | 0.79 | KMT2A (0.69) | ELANEKMT2AMAPTDAOALDH1A1 | |
| SCHEMBL124774 | 0.77 | RAB9A (0.54) | ELANEKMT2ADAONPC1CYP1A2 | |
| SCHEMBL2116925 | 0.75 | RAB9A (0.75) | KMT2ADAONPC1CYP1A2CYP2C19 | |
| Benzil SCHEMBL10422064 | 0.75 | DAO (0.69) | DAOKDM4E | |
| Kojic Acid SCHEMBL942734 | 0.75 | DAO (0.69) | DAOKDM4E | |
| SCHEMBL1686913 | 0.74 | KMT2A (0.48) | ELANEKMT2ADAONPC1CYP1A2 | |
| SCHEMBL10422065 | 0.74 | KMT2A (0.41) | ELANEKMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3569466 | 0.73 | DAO (0.56) | KMT2AMAPTDAOALDH1A1SMN1; SMN2 | |
| SCHEMBL5070268 | 0.73 | RAB9A (0.56) | ELANEKMT2AMAPTDAONPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200289392-A1 | A MELANOGENESIS INHIBITOR COMPOSITION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-09-17 | — | — | US | claimed |
| EP-3644947-A1 | A MELANOGENESIS INHIBITOR COMPOSITION | Dow Global Technologies LLC (US) | 2020-05-06 | — | — | EP | claimed |
| CN-110769808-A | Melanin production inhibitor composition | 陶氏环球技术有限责任公司 | 2020-02-07 | — | — | CN | claimed |
| WO-2019005437-A1 | A MELANOGENESIS INHIBITOR COMPOSITION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-01-03 | — | — | WO | claimed |
| EP-0308543-B1 | COMPOSITIONS FOR EXTERNAL APPLICATION | Sansho Seiyaku Co., Ltd. (JP) | 1993-09-22 | — | — | EP | claimed |
| US-4990330-A | Skin whitening and sunscreen; Kojic acid of esters, glucosamine and derivatives, cystein | SANSHO SEIYAKU CO., LTD. (JP) | 1991-02-05 | — | — | US | claimed |
| EP-0208799-B1 | WHITENING COSMETIC COMPOSITION | Sansho Seiyaku Co., Ltd. (JP) | 1990-09-26 | — | — | EP | claimed |
| US-4948577-A | KOJIC ACID AND 4-/1,1-DIMETHYLETHYL/-4'-METHOXY DIBENZOYLMETHANE; PREVENT COLORING OF SKIN WHEN EXPOSED TO ULTRAVIOLET LIGHT | SANSHO SEIYAKU CO., LTD. (JP) | 1990-08-14 | — | — | US | claimed |
| EP-0381057-A2 | Chemical composition for external application | Sansho Seiyaku Co., Ltd. (JP) | 1990-08-08 | — | — | EP | claimed |
| US-4919921-A | KOJIC ACID OR AN ESTER OF KOJIC ACID AND VITAMIN C OR A DERIVATIVE OF VITAMIN C | SANSHO SEIYAKU CO., LTD. (JP) | 1990-04-24 | — | — | US | claimed |
| EP-0308543-A1 | Compositions for external application | Sansho Seiyaku Co., Ltd. (JP) | 1989-03-29 | — | — | EP | claimed |
| EP-0308919-A1 | Compositions for topical use having melanin synthesis-inhibiting activity | Sansho Seiyaku Co., Ltd. (JP) | 1989-03-29 | — | — | EP | claimed |
| EP-0308918-A1 | Compositions for topical use having melanin synthesis-inhibiting activity | Sansho Seiyaku Co., Ltd. (JP) | 1989-03-29 | — | — | EP | claimed |
| WO-2024132395-A1 | COLOR STABILIZATION OF FORMULAE WITH AN INDOLE | UNILEVER IP HOLDINGS B.V. (NL) | 2024-06-27 | — | — | WO | disclosed |
| EP-4308071-A1 | USE OF HORDENINE FOR TREATING CELLULAR SENESCENCE | Unilever IP Holdings B.V. (NL) | 2024-01-24 | — | — | EP | disclosed |
| EP-4301328-A1 | USE OF FRUCTANS FOR PROVIDING SKIN CARE BENEFITS | Unilever IP Holdings B.V. (NL) | 2024-01-10 | — | — | EP | disclosed |
| EP-0308543-A1 | Compositions for external application | Sansho Seiyaku Co., Ltd. (JP) | 1989-03-29 | — | — | EP | disclosed |
| EP-0308919-A1 | Compositions for topical use having melanin synthesis-inhibiting activity | Sansho Seiyaku Co., Ltd. (JP) | 1989-03-29 | — | — | EP | disclosed |
| US-4696813-A | PLACENTA EXTRACT AND KOJIC ACID | SANSHO SEIYAKU CO., LTD. (JP) | 1987-09-29 | — | — | US | disclosed |
| EP-0208799-A1 | Whitening cosmetic composition | Sansho Seiyaku Co., Ltd. (JP) | 1987-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200289392-A1 | A MELANOGENESIS INHIBITOR COMPOSITION | TYR, MC1R, MITF | ELANE 3929/4885KMT2A 413/4885MAPT 2228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.