SCHEMBL9427604

SCHEMBL9427604

CCN(CC)c1ccc(N=C=S)cn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 1/20 0.50
P2RY6 Q15077 1/20 0.39
AOC3 Q16853 1/20 0.36
MYC P01106 9/20 0.35
MIF P14174 1/20 0.34
HCAR3 P49019 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
MEN1 O00255 2/20 0.32
MAPT P10636 2/20 0.32
KMT2A Q03164 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
LMNA P02545 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11708761 0.87 HCAR3 (0.48) GBA1P2RY6AOC3MIFHCAR3
SCHEMBL11710043 0.84 HCAR3 (0.39) GBA1P2RY6AOC3MIFHCAR3
SCHEMBL11708883 0.82 HCAR3 (0.38) GBA1P2RY6AOC3HCAR3MEN1
SCHEMBL2889749 0.81 P2RY6 (0.38) P2RY6MIFCA1CA2HSD17B10
SCHEMBL13531875 0.77 GBA1 (0.55) GBA1AOC3MYCHCAR3MEN1
SCHEMBL1456966 0.73 P2RY6 (0.50) P2RY6MIFGABRA1GABRB2MEN1
SCHEMBL11710623 0.72 MAPT (0.45) P2RY6MIFGABRA1GABRB2MEN1
SCHEMBL21518466 0.71 ADRA2A (0.50) P2RY6MIFKMT2ACYP1A2CA1
SCHEMBL30298639 0.71 ADRA2A (0.50) P2RY6MIFKMT2ACYP1A2CA1
SCHEMBL11709850 0.70 NPC1 (0.52) P2RY6MIFGABRA1GABRB2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5310724-A Pre- and postemergence; plant growth regulators FMC CORPORATION (US) 1994-05-10 US disclosed
US-5108486-A Herbicides KANAGAWA CHEMICAL LABORATORY, LTD. (JP) 1992-04-28 US disclosed
US-4001254-A ISOTHIOCYANOPYRIDINE DERIVATIVES CIBA-GEIGY CORPORATION (US) 1977-01-04 US disclosed